Triggering antitumoural drug release and gene expression by magnetic hyperthermia
M. Moros
1, 2
,
Javier Idiago López
1, 2
,
Laura Asin
1, 2
,
Eduardo Moreno Antolín
3
,
Lilianne Beola
3
,
V Grazú
1, 2
,
Raluca M. Fratila
1
,
Lucía Gutiérrez
4
,
Jesús Grajal de la Fuente
1, 2
1
3
Publication type: Journal Article
Publication date: 2019-01-01
scimago Q1
wos Q1
SJR: 3.721
CiteScore: 36.0
Impact factor: 17.6
ISSN: 0169409X, 18728294
PubMed ID:
30339825
Pharmaceutical Science
Abstract
Magnetic nanoparticles (MNPs) are promising tools for a wide array of biomedical applications. One of their most outstanding properties is the ability to generate heat when exposed to alternating magnetic fields, usually exploited in magnetic hyperthermia therapy of cancer. In this contribution, we provide a critical review of the use of MNPs and magnetic hyperthermia as drug release and gene expression triggers for cancer therapy. Several strategies for the release of chemotherapeutic drugs from thermo-responsive matrices are discussed, providing representative examples of their application at different levels (from proof of concept to in vivo applications). The potential of magnetic hyperthermia to promote in situ expression of therapeutic genes using vectors that contain heat-responsive promoters is also reviewed in the context of cancer gene therapy.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
Journal of Nanobiotechnology
4 publications, 3.39%
|
|
|
Nanoscale
4 publications, 3.39%
|
|
|
Journal of Drug Delivery Science and Technology
3 publications, 2.54%
|
|
|
Acta Biomaterialia
3 publications, 2.54%
|
|
|
ACS applied materials & interfaces
3 publications, 2.54%
|
|
|
ACS Applied Nano Materials
3 publications, 2.54%
|
|
|
ACS Applied Bio Materials
3 publications, 2.54%
|
|
|
Pharmaceutics
2 publications, 1.69%
|
|
|
Nanomedicine
2 publications, 1.69%
|
|
|
Bioengineering
2 publications, 1.69%
|
|
|
Journal of Nanoparticle Research
2 publications, 1.69%
|
|
|
Materials Today Chemistry
2 publications, 1.69%
|
|
|
Journal of Magnetism and Magnetic Materials
2 publications, 1.69%
|
|
|
Coordination Chemistry Reviews
2 publications, 1.69%
|
|
|
Advanced Functional Materials
2 publications, 1.69%
|
|
|
Expert Opinion on Drug Delivery
2 publications, 1.69%
|
|
|
RSC Advances
2 publications, 1.69%
|
|
|
Cancers
2 publications, 1.69%
|
|
|
Frontiers in Bioengineering and Biotechnology
2 publications, 1.69%
|
|
|
International Journal of Molecular Sciences
2 publications, 1.69%
|
|
|
Russian Chemical Bulletin
1 publication, 0.85%
|
|
|
Applied Physics Reviews
1 publication, 0.85%
|
|
|
Biological and Pharmaceutical Bulletin
1 publication, 0.85%
|
|
|
BMC Chemistry
1 publication, 0.85%
|
|
|
Physical Review Applied
1 publication, 0.85%
|
|
|
Nanomaterials
1 publication, 0.85%
|
|
|
Frontiers in Chemistry
1 publication, 0.85%
|
|
|
Science China Life Sciences
1 publication, 0.85%
|
|
|
Nature Communications
1 publication, 0.85%
|
|
|
1
2
3
4
|
Publishers
|
5
10
15
20
25
30
35
40
|
|
|
Elsevier
36 publications, 30.51%
|
|
|
American Chemical Society (ACS)
15 publications, 12.71%
|
|
|
Wiley
14 publications, 11.86%
|
|
|
Springer Nature
13 publications, 11.02%
|
|
|
Royal Society of Chemistry (RSC)
10 publications, 8.47%
|
|
|
MDPI
9 publications, 7.63%
|
|
|
Taylor & Francis
5 publications, 4.24%
|
|
|
Frontiers Media S.A.
3 publications, 2.54%
|
|
|
IOP Publishing
3 publications, 2.54%
|
|
|
Institute of Electrical and Electronics Engineers (IEEE)
2 publications, 1.69%
|
|
|
AIP Publishing
1 publication, 0.85%
|
|
|
Pharmaceutical Society of Japan
1 publication, 0.85%
|
|
|
American Physical Society (APS)
1 publication, 0.85%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 0.85%
|
|
|
Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
1 publication, 0.85%
|
|
|
Bentham Science Publishers Ltd.
1 publication, 0.85%
|
|
|
Science in China Press
1 publication, 0.85%
|
|
|
5
10
15
20
25
30
35
40
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
118
Total citations:
118
Citations from 2025:
21
(17.79%)
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Moros M. et al. Triggering antitumoural drug release and gene expression by magnetic hyperthermia // Advanced Drug Delivery Reviews. 2019. Vol. 138. pp. 326-343.
GOST all authors (up to 50)
Copy
Moros M., Idiago López J., Asin L., Moreno Antolín E., Beola L., Grazú V., Fratila R. M., Gutiérrez L., de la Fuente J. G. Triggering antitumoural drug release and gene expression by magnetic hyperthermia // Advanced Drug Delivery Reviews. 2019. Vol. 138. pp. 326-343.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.addr.2018.10.004
UR - https://doi.org/10.1016/j.addr.2018.10.004
TI - Triggering antitumoural drug release and gene expression by magnetic hyperthermia
T2 - Advanced Drug Delivery Reviews
AU - Moros, M.
AU - Idiago López, Javier
AU - Asin, Laura
AU - Moreno Antolín, Eduardo
AU - Beola, Lilianne
AU - Grazú, V
AU - Fratila, Raluca M.
AU - Gutiérrez, Lucía
AU - de la Fuente, Jesús Grajal
PY - 2019
DA - 2019/01/01
PB - Elsevier
SP - 326-343
VL - 138
PMID - 30339825
SN - 0169-409X
SN - 1872-8294
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Moros,
author = {M. Moros and Javier Idiago López and Laura Asin and Eduardo Moreno Antolín and Lilianne Beola and V Grazú and Raluca M. Fratila and Lucía Gutiérrez and Jesús Grajal de la Fuente},
title = {Triggering antitumoural drug release and gene expression by magnetic hyperthermia},
journal = {Advanced Drug Delivery Reviews},
year = {2019},
volume = {138},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.addr.2018.10.004},
pages = {326--343},
doi = {10.1016/j.addr.2018.10.004}
}