Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line
Fatima Ezzahra Bennani
1
,
Latifa Doudach
2
,
Y. Cherrah
3
,
Youssef Ramli
1
,
Khalid Karrouchi
1
,
M'hammed Ansar
1
,
My El Abbes Faouzi
3
Publication type: Journal Article
Publication date: 2020-04-01
scimago Q1
wos Q1
SJR: 0.786
CiteScore: 8.3
Impact factor: 4.7
ISSN: 00452068, 10902120
PubMed ID:
32120072
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Abstract
Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C3H3N2H.The presence of this nucleus in pharmacological agents of various therapeutic categories gifts a broad spectrum of biological activities and pharmaceuticals that contain pyrazole like celecoxib (anti-inflammatory), CDPPB (antipsychotic), Rimonabant (anti-obesity), Difenamizole, (Analgesic), Betazole (H2 receptor agonist), Fezolamide (Antidepressant), etc… The pharmacological potential of the pyrazole fraction is proved in many publication where they synthesized and evaluated pyrazoles against several biological agents. The aim of this article review is to survey recent works linking pyrazole structures to anticancer activities corresponding to 9 different type of cancer.
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272
Total citations:
272
Citations from 2025:
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(28.42%)
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Bennani F. E. et al. Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line // Bioorganic Chemistry. 2020. Vol. 97. p. 103470.
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Bennani F. E., Doudach L., Cherrah Y., Ramli Y., Karrouchi K., Ansar M., Faouzi M. E. A. Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line // Bioorganic Chemistry. 2020. Vol. 97. p. 103470.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.bioorg.2019.103470
UR - https://doi.org/10.1016/j.bioorg.2019.103470
TI - Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line
T2 - Bioorganic Chemistry
AU - Bennani, Fatima Ezzahra
AU - Doudach, Latifa
AU - Cherrah, Y.
AU - Ramli, Youssef
AU - Karrouchi, Khalid
AU - Ansar, M'hammed
AU - Faouzi, My El Abbes
PY - 2020
DA - 2020/04/01
PB - Elsevier
SP - 103470
VL - 97
PMID - 32120072
SN - 0045-2068
SN - 1090-2120
ER -
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@article{2020_Bennani,
author = {Fatima Ezzahra Bennani and Latifa Doudach and Y. Cherrah and Youssef Ramli and Khalid Karrouchi and M'hammed Ansar and My El Abbes Faouzi},
title = {Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line},
journal = {Bioorganic Chemistry},
year = {2020},
volume = {97},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/j.bioorg.2019.103470},
pages = {103470},
doi = {10.1016/j.bioorg.2019.103470}
}