Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity
Publication type: Journal Article
Publication date: 2008-04-01
scimago Q2
wos Q1
SJR: 0.608
CiteScore: 6.7
Impact factor: 3.0
ISSN: 09680896, 14643391
PubMed ID:
18248996
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Abstract
A new molecular modelling approach based on physico-chemical and pharmacokinetic properties, called Volsurf plus, was used to design new heterocyclic compounds with antiproliferative activity. The synthesis and in vitro antitumour tests on a breast carcinoma cell line (MCF7) confirmed VOLSURF predicted activity values.
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74
Total citations:
74
Citations from 2025:
1
(1.35%)
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MLA
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GOST
Copy
Fortuna C. G. et al. Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity // Bioorganic and Medicinal Chemistry. 2008. Vol. 16. No. 7. pp. 4150-4159.
GOST all authors (up to 50)
Copy
Fortuna C. G., Barresi V., Berellini G., Musumarra G. Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity // Bioorganic and Medicinal Chemistry. 2008. Vol. 16. No. 7. pp. 4150-4159.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.bmc.2007.12.042
UR - https://doi.org/10.1016/j.bmc.2007.12.042
TI - Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity
T2 - Bioorganic and Medicinal Chemistry
AU - Fortuna, Cosimo G.
AU - Barresi, Vincenza
AU - Berellini, Giuliano
AU - Musumarra, Giuseppe
PY - 2008
DA - 2008/04/01
PB - Elsevier
SP - 4150-4159
IS - 7
VL - 16
PMID - 18248996
SN - 0968-0896
SN - 1464-3391
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2008_Fortuna,
author = {Cosimo G. Fortuna and Vincenza Barresi and Giuliano Berellini and Giuseppe Musumarra},
title = {Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity},
journal = {Bioorganic and Medicinal Chemistry},
year = {2008},
volume = {16},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/j.bmc.2007.12.042},
number = {7},
pages = {4150--4159},
doi = {10.1016/j.bmc.2007.12.042}
}
Cite this
MLA
Copy
Fortuna, Cosimo G., et al. “Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity.” Bioorganic and Medicinal Chemistry, vol. 16, no. 7, Apr. 2008, pp. 4150-4159. https://doi.org/10.1016/j.bmc.2007.12.042.