Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs
Kouatli Omar
1
,
Panagiotis Zoumpoulakis
2
,
Charalabos Camoutsis
3
,
Marina Soković
4
,
Ana Ćirić
4
,
4
Department of Plant Physiology, Mycological Laboratory, Institute of Biological Research, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia
|
Publication type: Journal Article
Publication date: 2010-01-01
scimago Q2
wos Q1
SJR: 0.608
CiteScore: 6.7
Impact factor: 3.0
ISSN: 09680896, 14643391
PubMed ID:
19914077
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Abstract
As part of ongoing studies in developing new antimicrobials, a class of structurally novel 4-thiazolidinone derivatives incorporating three known bioactive nuclei such as thiazole, thiazolidinone and adamantane was synthesized by the multi-step reaction protocol, already reported in the literature. NMR and Molecular Modeling techniques were employed for structure elucidation and Z/E potential isomerism configuration of the analogues. Evaluation of antibacterial and antifungal activity showed that almost all compounds exhibited better results than reference drugs thus they could be promising candidates for novel drugs.
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GOST
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Omar K. et al. Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs // Bioorganic and Medicinal Chemistry. 2010. Vol. 18. No. 1. pp. 426-432.
GOST all authors (up to 50)
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Omar K., Geronikaki A., Zoumpoulakis P., Camoutsis C., Soković M., Ćirić A., Glamočlija J. Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs // Bioorganic and Medicinal Chemistry. 2010. Vol. 18. No. 1. pp. 426-432.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.bmc.2009.10.041
UR - https://doi.org/10.1016/j.bmc.2009.10.041
TI - Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs
T2 - Bioorganic and Medicinal Chemistry
AU - Omar, Kouatli
AU - Geronikaki, Athina
AU - Zoumpoulakis, Panagiotis
AU - Camoutsis, Charalabos
AU - Soković, Marina
AU - Ćirić, Ana
AU - Glamočlija, Jasmina
PY - 2010
DA - 2010/01/01
PB - Elsevier
SP - 426-432
IS - 1
VL - 18
PMID - 19914077
SN - 0968-0896
SN - 1464-3391
ER -
Cite this
BibTex (up to 50 authors)
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@article{2010_Omar,
author = {Kouatli Omar and Athina Geronikaki and Panagiotis Zoumpoulakis and Charalabos Camoutsis and Marina Soković and Ana Ćirić and Jasmina Glamočlija},
title = {Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs},
journal = {Bioorganic and Medicinal Chemistry},
year = {2010},
volume = {18},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.bmc.2009.10.041},
number = {1},
pages = {426--432},
doi = {10.1016/j.bmc.2009.10.041}
}
Cite this
MLA
Copy
Omar, Kouatli, et al. “Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs.” Bioorganic and Medicinal Chemistry, vol. 18, no. 1, Jan. 2010, pp. 426-432. https://doi.org/10.1016/j.bmc.2009.10.041.
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