Functionalization of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) core
Publication type: Journal Article
Publication date: 2008-05-01
scimago Q2
wos Q2
SJR: 0.472
CiteScore: 5.1
Impact factor: 2.2
ISSN: 0960894X, 14643405
PubMed ID:
18037291
Organic Chemistry
Drug Discovery
Biochemistry
Molecular Biology
Pharmaceutical Science
Clinical Biochemistry
Molecular Medicine
Abstract
The new BODIPY systems 1 and 2 were prepared and then used as substrates to explore S(N)Ar and F-B displacement reactions. Chloride was easily displaced from 1 by a piperidine/ester, methylmagnesium bromide selectively displaced fluoride, and cyanide could attack both sites. System 2 readily added soft nucleophiles to the electrophilic carbon atoms, providing a new method for bioconjugation of BODIPYs to proteins while also introducing a (19)F probe.
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156
Total citations:
156
Citations from 2024:
8
(5.13%)
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GOST
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Li L., Nguyen B. T. T., Burgess K. Functionalization of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) core // Bioorganic and Medicinal Chemistry Letters. 2008. Vol. 18. No. 10. pp. 3112-3116.
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Li L., Nguyen B. T. T., Burgess K. Functionalization of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) core // Bioorganic and Medicinal Chemistry Letters. 2008. Vol. 18. No. 10. pp. 3112-3116.
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RIS
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TY - JOUR
DO - 10.1016/j.bmcl.2007.10.103
UR - https://doi.org/10.1016/j.bmcl.2007.10.103
TI - Functionalization of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) core
T2 - Bioorganic and Medicinal Chemistry Letters
AU - Li, Lingling
AU - Nguyen, Binh T. T.
AU - Burgess, Kevin
PY - 2008
DA - 2008/05/01
PB - Elsevier
SP - 3112-3116
IS - 10
VL - 18
PMID - 18037291
SN - 0960-894X
SN - 1464-3405
ER -
Cite this
BibTex (up to 50 authors)
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@article{2008_Li,
author = {Lingling Li and Binh T. T. Nguyen and Kevin Burgess},
title = {Functionalization of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) core},
journal = {Bioorganic and Medicinal Chemistry Letters},
year = {2008},
volume = {18},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.bmcl.2007.10.103},
number = {10},
pages = {3112--3116},
doi = {10.1016/j.bmcl.2007.10.103}
}
Cite this
MLA
Copy
Li, Lingling, et al. “Functionalization of the 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) core.” Bioorganic and Medicinal Chemistry Letters, vol. 18, no. 10, May. 2008, pp. 3112-3116. https://doi.org/10.1016/j.bmcl.2007.10.103.