Bioorganic and Medicinal Chemistry Letters

, том 18 , издание 11 , страницы 3310-3314

The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives

Тип публикации: Journal Article

Дата публикации: 2008-06-01

Elsevier

Bioorganic and Medicinal Chemistry Letters

scimago Q2

wos Q2

БС2

SJR: 0.472

CiteScore: 5.1

Impact factor: 2.2

ISSN: 0960894X, 14643405

DOI: 10.1016/j.bmcl.2008.04.032

Скопировать DOI

PubMed ID: 18440813

Organic Chemistry

Drug Discovery

Biochemistry

Molecular Biology

Pharmaceutical Science

Clinical Biochemistry

Molecular Medicine

Краткое описание

Benzimidazolone derivatives were discovered as novel CB2 selective agonists. Structure Activity Relationship (SAR) studies around them were examined to improve metabolic stability. Compound 39 exhibited excellent metabolic stability in human liver microsomes (HLM) and significant attenuation of the chronic colonic allodynia in the TNBS-treated rats by po administration.

Найдено

Для доступа к списку цитирований публикации необходимо авторизоваться.

Войти с ORCID

Для доступа к списку профилей, цитирующих публикацию, необходимо авторизоваться.

Войти с ORCID

Топ-30

Журналы

Издатели

	1 2 3 4 5 6 7 8 9
Elsevier	Elsevier, 9, 32.14% Elsevier 9 публикаций, 32.14%
American Chemical Society (ACS)	American Chemical Society (ACS), 8, 28.57% American Chemical Society (ACS) 8 публикаций, 28.57%
Taylor & Francis	Taylor & Francis, 3, 10.71% Taylor & Francis 3 публикации, 10.71%
Wiley	Wiley, 2, 7.14% Wiley 2 публикации, 7.14%
S. Karger AG	S. Karger AG, 1, 3.57% S. Karger AG 1 публикация, 3.57%
SAGE	SAGE, 1, 3.57% SAGE 1 публикация, 3.57%
MDPI	MDPI, 1, 3.57% MDPI 1 публикация, 3.57%
Springer Nature	Springer Nature, 1, 3.57% Springer Nature 1 публикация, 3.57%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 3.57% Royal Society of Chemistry (RSC) 1 публикация, 3.57%
Pleiades Publishing	Pleiades Publishing, 1, 3.57% Pleiades Publishing 1 публикация, 3.57%
	1 2 3 4 5 6 7 8 9

Мы не учитываем публикации, у которых нет DOI.
Статистика публикаций обновляется еженедельно.

Вы ученый?

Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.

Войти с ORCID

Метрики

Цитировать

ГОСТ |

Цитировать

ГОСТ Скопировать

Omura H. et al. The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives // Bioorganic and Medicinal Chemistry Letters. 2008. Vol. 18. No. 11. pp. 3310-3314.

ГОСТ со всеми авторами (до 50) Скопировать

Omura H., KAWAI M., Shima A., Iwata Y., Ito F., Masuda T., Ohta A., Makita N., Omoto K., Sugimoto H., KIKUCHI A., Iwata H., Ando K. The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives // Bioorganic and Medicinal Chemistry Letters. 2008. Vol. 18. No. 11. pp. 3310-3314.

RIS |

Цитировать

RIS Скопировать

TY - JOUR

DO - 10.1016/j.bmcl.2008.04.032

UR - https://doi.org/10.1016/j.bmcl.2008.04.032

TI - The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives

T2 - Bioorganic and Medicinal Chemistry Letters

AU - Omura, Hirofumi

AU - KAWAI, Makoto

AU - Shima, Akiko

AU - Iwata, Yasuhiro

AU - Ito, Fumitaka

AU - Masuda, Tsutomu

AU - Ohta, Atsuko

AU - Makita, Naoya

AU - Omoto, Kiyoyuki

AU - Sugimoto, Hiromi

AU - KIKUCHI, Akira

AU - Iwata, Hiroshi

AU - Ando, Kazuo

PY - 2008

DA - 2008/06/01

PB - Elsevier

SP - 3310-3314

IS - 11

VL - 18

PMID - 18440813

SN - 0960-894X

SN - 1464-3405

ER -

BibTex |

Цитировать

BibTex (до 50 авторов) Скопировать

@article{2008_Omura,

author = {Hirofumi Omura and Makoto KAWAI and Akiko Shima and Yasuhiro Iwata and Fumitaka Ito and Tsutomu Masuda and Atsuko Ohta and Naoya Makita and Kiyoyuki Omoto and Hiromi Sugimoto and Akira KIKUCHI and Hiroshi Iwata and Kazuo Ando},

title = {The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives},

journal = {Bioorganic and Medicinal Chemistry Letters},

year = {2008},

volume = {18},

publisher = {Elsevier},

month = {jun},

url = {https://doi.org/10.1016/j.bmcl.2008.04.032},

number = {11},

pages = {3310--3314},

doi = {10.1016/j.bmcl.2008.04.032}

}

MLA

Цитировать

MLA Скопировать

Omura, Hirofumi, et al. “The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives.” Bioorganic and Medicinal Chemistry Letters, vol. 18, no. 11, Jun. 2008, pp. 3310-3314. https://doi.org/10.1016/j.bmcl.2008.04.032.

Издатель

Elsevier

Журнал

Bioorganic and Medicinal Chemistry Letters

scimago Q2

wos Q2

БС2

SJR

0.472

CiteScore

5.1

Impact factor

2.2

ISSN

0960894X (Print)

14643405 (Electronic)