High-performance nonenzymatic electrochemical glucose biosensor based on AgNP-decorated MoS2 microflowers

A facile hydrothermal route was used to synthesize silver nanoparticle (AgNP)-decorated microflower molybdenum disulfide (MoS 2 -MF) for bio-electrochemical platform fabrication to detect nonenzymatic glucose concentration. The morphologies of the materials were studied by scanning electron microscopy, and their structural characteristics were analyzed by X-ray diffractometry and energy-dispersive X-ray spectroscopy. The electrochemical characteristics of the AgNPs/MoS 2 -MF/PtE biosensor were studied by cyclic voltammetry. The obtained data indicated that the developed nonenzymatic glucose sensor has a large linear response between 1.0 and 15.0 mM, a limit of detection of as low as 1.0 mM, and a sensitivity of 46.5 μA nM −1 cm −2 . The biosensor also displayed outstanding selectivity, stability, reproducibility, and repeatability. Additionally, the AgNPs/MoS 2 -MF/PtE biosensor was utilized to detect glucose concentration in real sample and showed practical application potential for glucose detection. • Silver nanoparticle-decorated molybdenum disulfide microflower was synthesized for nonenzyme glucose biosensor. • A fast electron transfer on the interface of AgNP and MoS 2 was generated for biosensor. • The nonenzymatic biosensor exhibited good application in glucose concentration detection in real sample.