Bismuth(III) complexes with aminopolycarboxylate and polyaminopolycarboxylate ligands: Chemistry and structure

This review concerns data on the chemistry and structures of bismuth(III) complexes with aminopolycarboxylate (APC) and polyaminopolycarboxylate (PAPC) ligands. In aqueous solutions Bi(III) binds strongly to both APC and PAPC ligands. Recently these ligands have been considered for bismuth radioisotope chelation in regards to their use in nuclear medicine. The solid state structures of Bi(III) coordination compounds with APC and PAPC ligands are governed mainly by three considerations: (i) low-dentate ligands lead to strong interactions between Bi atoms and donor atoms on the neighboring complexes which often produce oligomeric and polymeric structures; (ii) increasing the number of donor atoms in the ligands and the presence of additional ligands in the coordination sphere of Bi atom leads preferentially to monomeric structures; (iii) the presence of bridging carboxylate groups leads to different nuclearities, from dimers to infinite structures. Several aspects of recent applications of Bi(III) APC and PAPC complexes are also discussed.