Ceramics International

, том 42 , издание 15 , страницы 17310-17316

Zinc-releasing calcium phosphate cements for bone substitute materials

V. Graziani ¹

M Fosca ¹

A. A. Egorov ²

Yu V Zobkov ²

A Yu Fedotov ²

Alexander E Baranchikov ³

M. A. Ortenzi ¹

RUGGERO CAMINITI ⁴

Vladimir S. Komlev ²

Julietta V. Rau ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 4 аффилиации

Istituto di Struttura della Materia, Consiglio Nazionale delle Ricerche, CNR-ISM, Via del Fosso del Cavaliere, Rome, 100-00133 Italy |

A.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, Moscow, 119991 Russia |

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninsky prospect, 31, Moscow 119991, Russia |

⁴

Dipartimento di Chimica, Università di Roma “La Sapienza”, Piazzale Aldo Moro, Rome, 5-00185 Italy

Римский Университет Ла Сапиенца

Университет имени Альдо Моро в Бари

Тип публикации: Journal Article

Дата публикации: 2016-11-01

Elsevier

Ceramics International

scimago Q1

wos Q1

БС1

SJR: 1.034

CiteScore: 9.1

Impact factor: 5.6

ISSN: 02728842, 18733956

DOI: 10.1016/j.ceramint.2016.08.027

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Materials Chemistry

Surfaces, Coatings and Films

Ceramics and Composites

Electronic, Optical and Magnetic Materials

Process Chemistry and Technology

Краткое описание

Abstract The goal of the present study was to develop zinc-doped calcium phosphate bone cements (CPCs-Zn) for functionalized bone grafts applications. An aqueous co-precipitation process for synthesis of β-tricalcium phosphate (β-TCP) powder samples with Zn addition ranging from 0 wt% up to 1.2 wt% was proposed as an alternative approach to produce CPCs-Zn, instead of mechanical mixing of powders. Real-time monitoring of structural transformations and kinetics of CPCs-Zn (Zn=0 wt%, 0.6 wt% and 1.2 wt%) was carried out by the Energy Dispersive X-Ray Diffraction technique. The microstructure development in CPCs-Zn was investigated by Scanning Electron Microscopy. Zn-ion release from CPC-Zn 0.6 wt% and CPC-Zn 1.2 wt% cements, measured by the Atomic Emission Spectroscopy, corresponded to the average values of 0.30±0.01 and 0.10±0.01 µg/L, respectively. The results of antibacterial tests proved the inhibitory effect towards pathogenic Escherichia coli only for the CPC-Zn 0.6 wt% cement formulation.

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Graziani V. et al. Zinc-releasing calcium phosphate cements for bone substitute materials // Ceramics International. 2016. Vol. 42. No. 15. pp. 17310-17316.

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Graziani V., Fosca M., Egorov A. A., Zobkov Yu. V., Fedotov A. Yu., Baranchikov A. E., Ortenzi M. A., CAMINITI R., Komlev V. S., Rau J. V. Zinc-releasing calcium phosphate cements for bone substitute materials // Ceramics International. 2016. Vol. 42. No. 15. pp. 17310-17316.

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TY - JOUR

DO - 10.1016/j.ceramint.2016.08.027

UR - https://linkinghub.elsevier.com/retrieve/pii/S0272884216313360

TI - Zinc-releasing calcium phosphate cements for bone substitute materials

T2 - Ceramics International

AU - Graziani, V.

AU - Fosca, M

AU - Egorov, A. A.

AU - Zobkov, Yu V

AU - Fedotov, A Yu

AU - Baranchikov, Alexander E

AU - Ortenzi, M. A.

AU - CAMINITI, RUGGERO

AU - Komlev, Vladimir S.

AU - Rau, Julietta V.

PY - 2016

DA - 2016/11/01

PB - Elsevier

SP - 17310-17316

IS - 15

VL - 42

SN - 0272-8842

SN - 1873-3956

ER -

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@article{2016_Graziani,

author = {V. Graziani and M Fosca and A. A. Egorov and Yu V Zobkov and A Yu Fedotov and Alexander E Baranchikov and M. A. Ortenzi and RUGGERO CAMINITI and Vladimir S. Komlev and Julietta V. Rau},

title = {Zinc-releasing calcium phosphate cements for bone substitute materials},

journal = {Ceramics International},

year = {2016},

volume = {42},

publisher = {Elsevier},

month = {nov},

url = {https://linkinghub.elsevier.com/retrieve/pii/S0272884216313360},

number = {15},

pages = {17310--17316},

doi = {10.1016/j.ceramint.2016.08.027}

}

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Graziani, V., et al. “Zinc-releasing calcium phosphate cements for bone substitute materials.” Ceramics International, vol. 42, no. 15, Nov. 2016, pp. 17310-17316. https://linkinghub.elsevier.com/retrieve/pii/S0272884216313360.