Advances in Colloid and Interface Science

, volume 249 , pages 331-345

Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents

A. Angelova ¹

Vasil M. Garamus ²

Borislav Angelov ³

Hide authors affiliations Show authors affiliations: 3 affiliations

Institut Galien Paris-Sud, CNRS UMR 8612, Univ. Paris-Sud, Université Paris-Saclay, LabEx LERMIT, F-92290 Châtenay-Malabry cedex, France. |

Helmholtz-Zentrum Geesthacht: Centre for Materials and Coastal Research, D-21502 Geesthacht, Germany. |

Institute of Physics, ELI Beamlines, Academy of Sciences of the Czech Republic, Na Slovance 2, CZ-18221 Prague, Czech Republic. |

Publication type: Journal Article

Publication date: 2017-11-01

Elsevier

Advances in Colloid and Interface Science

scimago Q1

wos Q1

SJR: 3.090

CiteScore: 29.7

Impact factor: 19.3

ISSN: 00018686, 18733727

DOI: 10.1016/j.cis.2017.04.006

Copy DOI

PubMed ID: 28477868

Physical and Theoretical Chemistry

Colloid and Surface Chemistry

Surfaces and Interfaces

Abstract

The present work highlights recent achievements in development of nanostructured dispersions and biocolloids for drug delivery applications. We emphasize the key role of biological small-angle X-ray scattering (BioSAXS) investigations for the nanomedicine design. A focus is given on controlled encapsulation of small molecular weight phytochemical drugs in lipid-based nanocarriers as well as on encapsulation of macromolecular siRNA, plasmid DNA, peptide and protein pharmaceuticals in nanostructured nanoparticles that may provide efficient intracellular delivery and triggered drug release. Selected examples of utilisation of the BioSAXS method for characterization of various types of liquid crystalline nanoorganizations (liposome, spongosome, cubosome, hexosome, and nanostructured lipid carriers) are discussed in view of the successful encapsulation and protection of phytochemicals and therapeutic biomolecules in the hydrophobic or the hydrophilic compartments of the nanocarriers. We conclude that the structural design of the nanoparticulate carriers is of crucial importance for the therapeutic outcome and the triggered drug release from biocolloids.

Found

1 citation

Kuzmin Vladimir

394 publications, 2 929 citations

h-index: 27

Emanuel Institute of Biochemical Physics of the Russian Academy of Sciences

1 citation

Airaksinen Anu

96 publications, 3 118 citations, 43 reviews

h-index: 31

University of Turku

Turku PET Centre

1 citation

Rajendran Jagathesh

34 publications, 1 843 citations, 8 reviews

h-index: 22

Top-30

Journals

	2 4 6 8 10 12 14
Langmuir	Langmuir, 14, 7.29% Langmuir 14 publications, 7.29%
Nanomaterials	Nanomaterials, 9, 4.69% Nanomaterials 9 publications, 4.69%
Journal of Colloid and Interface Science	Journal of Colloid and Interface Science, 9, 4.69% Journal of Colloid and Interface Science 9 publications, 4.69%
Colloids and Surfaces B: Biointerfaces	Colloids and Surfaces B: Biointerfaces, 8, 4.17% Colloids and Surfaces B: Biointerfaces 8 publications, 4.17%
Journal of Drug Delivery Science and Technology	Journal of Drug Delivery Science and Technology, 7, 3.65% Journal of Drug Delivery Science and Technology 7 publications, 3.65%
Molecules	Molecules, 5, 2.6% Molecules 5 publications, 2.6%
Current Opinion in Colloid and Interface Science	Current Opinion in Colloid and Interface Science, 5, 2.6% Current Opinion in Colloid and Interface Science 5 publications, 2.6%
Pharmaceutics	Pharmaceutics, 4, 2.08% Pharmaceutics 4 publications, 2.08%
International Journal of Pharmaceutics	International Journal of Pharmaceutics, 4, 2.08% International Journal of Pharmaceutics 4 publications, 2.08%
Journal of Molecular Liquids	Journal of Molecular Liquids, 4, 2.08% Journal of Molecular Liquids 4 publications, 2.08%
ACS applied materials & interfaces	ACS applied materials & interfaces, 4, 2.08% ACS applied materials & interfaces 4 publications, 2.08%
Journal of Materials Chemistry B	Journal of Materials Chemistry B, 4, 2.08% Journal of Materials Chemistry B 4 publications, 2.08%
Nanomedicine	Nanomedicine, 3, 1.56% Nanomedicine 3 publications, 1.56%
Journal of Controlled Release	Journal of Controlled Release, 3, 1.56% Journal of Controlled Release 3 publications, 1.56%
Advances in Colloid and Interface Science	Advances in Colloid and Interface Science, 3, 1.56% Advances in Colloid and Interface Science 3 publications, 1.56%
ACS Sustainable Chemistry and Engineering	ACS Sustainable Chemistry and Engineering, 3, 1.56% ACS Sustainable Chemistry and Engineering 3 publications, 1.56%
ACS Omega	ACS Omega, 3, 1.56% ACS Omega 3 publications, 1.56%
Physical Chemistry Chemical Physics	Physical Chemistry Chemical Physics, 3, 1.56% Physical Chemistry Chemical Physics 3 publications, 1.56%
ACS Nano	ACS Nano, 3, 1.56% ACS Nano 3 publications, 1.56%
Pharmaceuticals	Pharmaceuticals, 2, 1.04% Pharmaceuticals 2 publications, 1.04%
Colloids and Surfaces A: Physicochemical and Engineering Aspects	Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2, 1.04% Colloids and Surfaces A: Physicochemical and Engineering Aspects 2 publications, 1.04%
Journal of Molecular Structure	Journal of Molecular Structure, 2, 1.04% Journal of Molecular Structure 2 publications, 1.04%
Biomedicine and Pharmacotherapy	Biomedicine and Pharmacotherapy, 2, 1.04% Biomedicine and Pharmacotherapy 2 publications, 1.04%
Chemistry and Physics of Lipids	Chemistry and Physics of Lipids, 2, 1.04% Chemistry and Physics of Lipids 2 publications, 1.04%
Molecular Pharmaceutics	Molecular Pharmaceutics, 2, 1.04% Molecular Pharmaceutics 2 publications, 1.04%
RSC Advances	RSC Advances, 2, 1.04% RSC Advances 2 publications, 1.04%
Journal of Drug Targeting	Journal of Drug Targeting, 2, 1.04% Journal of Drug Targeting 2 publications, 1.04%
Journal of Dispersion Science and Technology	Journal of Dispersion Science and Technology, 2, 1.04% Journal of Dispersion Science and Technology 2 publications, 1.04%
Advanced Functional Materials	Advanced Functional Materials, 2, 1.04% Advanced Functional Materials 2 publications, 1.04%
	2 4 6 8 10 12 14

Publishers

	10 20 30 40 50 60 70 80
Elsevier	Elsevier, 75, 39.06% Elsevier 75 publications, 39.06%
American Chemical Society (ACS)	American Chemical Society (ACS), 30, 15.63% American Chemical Society (ACS) 30 publications, 15.63%
MDPI	MDPI, 24, 12.5% MDPI 24 publications, 12.5%
Taylor & Francis	Taylor & Francis, 13, 6.77% Taylor & Francis 13 publications, 6.77%
Springer Nature	Springer Nature, 13, 6.77% Springer Nature 13 publications, 6.77%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 12, 6.25% Royal Society of Chemistry (RSC) 12 publications, 6.25%
Wiley	Wiley, 11, 5.73% Wiley 11 publications, 5.73%
Frontiers Media S.A.	Frontiers Media S.A., 2, 1.04% Frontiers Media S.A. 2 publications, 1.04%
Walter de Gruyter	Walter de Gruyter, 2, 1.04% Walter de Gruyter 2 publications, 1.04%
Bentham Science Publishers Ltd.	Bentham Science Publishers Ltd., 2, 1.04% Bentham Science Publishers Ltd. 2 publications, 1.04%
Oxford University Press	Oxford University Press, 1, 0.52% Oxford University Press 1 publication, 0.52%
Institute of Molecular Biology and Genetics (NAS Ukraine)	Institute of Molecular Biology and Genetics (NAS Ukraine), 1, 0.52% Institute of Molecular Biology and Genetics (NAS Ukraine) 1 publication, 0.52%
OOO Zhurnal "Mendeleevskie Soobshcheniya"	OOO Zhurnal "Mendeleevskie Soobshcheniya", 1, 0.52% OOO Zhurnal "Mendeleevskie Soobshcheniya" 1 publication, 0.52%
IGI Global	IGI Global, 1, 0.52% IGI Global 1 publication, 0.52%
Pleiades Publishing	Pleiades Publishing, 1, 0.52% Pleiades Publishing 1 publication, 0.52%
The Russian Academy of Sciences	The Russian Academy of Sciences, 1, 0.52% The Russian Academy of Sciences 1 publication, 0.52%
	10 20 30 40 50 60 70 80

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

Metrics

192

Cite this

GOST |

Cite this

GOST Copy

Angelova A. et al. Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents // Advances in Colloid and Interface Science. 2017. Vol. 249. pp. 331-345.

GOST all authors (up to 50) Copy

Angelova A., Garamus V. M., Angelov B. Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents // Advances in Colloid and Interface Science. 2017. Vol. 249. pp. 331-345.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.cis.2017.04.006

UR - https://doi.org/10.1016/j.cis.2017.04.006

TI - Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents

T2 - Advances in Colloid and Interface Science

AU - Angelova, A.

AU - Garamus, Vasil M.

AU - Angelov, Borislav

PY - 2017

DA - 2017/11/01

PB - Elsevier

SP - 331-345

VL - 249

PMID - 28477868

SN - 0001-8686

SN - 1873-3727

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2017_Angelova,

author = {A. Angelova and Vasil M. Garamus and Borislav Angelov},

title = {Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents},

journal = {Advances in Colloid and Interface Science},

year = {2017},

volume = {249},

publisher = {Elsevier},

month = {nov},

url = {https://doi.org/10.1016/j.cis.2017.04.006},

pages = {331--345},

doi = {10.1016/j.cis.2017.04.006}

}

Publisher

Elsevier

Journal

Advances in Colloid and Interface Science

scimago Q1

wos Q1

SJR

3.090

CiteScore

29.7

Impact factor

19.3

ISSN

00018686 (Print)

18733727