Environmental Toxicology and Pharmacology

, volume 101 , pages 104194

Co-exposure of polycarbonate microplastics aggravated the toxic effects of imidacloprid on the liver and gut microbiota in mice

李娇 Li Jiao ^{1, 2}

Jie Liu ³

Li Zhai ⁴

Kun Lu ⁵

Hide authors affiliations Show authors affiliations: 5 affiliations

Nanjing Medical University, Nanjing 210029, China |

Nanjing Qixia District Hospital, Nanjing 210033, China |

Clinical Oncology School of Fujian Medical University, Department of radiology, Fujian Cancer Hospital, Fuzhou 350000, China |

⁴

Department of Chemistry, City University of Hong Kong, Hong Kong, China |

⁵

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China |

Publication type: Journal Article

Publication date: 2023-08-01

Elsevier

Environmental Toxicology and Pharmacology

scimago Q1

wos Q1

SJR: 1.064

CiteScore: 7.9

Impact factor: 4.2

ISSN: 13826689, 18727077

DOI: 10.1016/j.etap.2023.104194

Copy DOI

PubMed ID: 37348773

General Medicine

Pharmacology

Health, Toxicology and Mutagenesis

Toxicology

Abstract

The joint toxicity of microplastics (MPs) and pesticides may be different from MPs or pesticides individually, however, the information about the combined toxicity of MPs and pesticides is not well understood. Herein, we investigated the joint toxicity of polycarbonate (PC) MPs and imidacloprid (IMI) on mice. After orally exposure for 4 weeks, PC and/or IMI lowered the body weight gain of mice. Single exposure of IMI induced the tissue damage in liver by disturbing the redox homeostasis, and PC significantly aggravated the imbalance of redox homeostasis by facilitating the accumulation of IMI in liver. Additionally, compared to single exposure of PC or IMI, PC+IMI exposure caused more severe damage to the gut microstructure and microbial diversity. Several key metabolic pathways, especially the lipid metabolism, were significantly affected. Overall, these findings provide new insight into understanding the potential risk of co-exposure of microplastics and pesticides to animal and human health.

Found

1 citation

Nasibulin Albert

🥼 🤝

DSc in Chemistry, professor

464 publications, 13 660 citations, 9 reviews

h-index: 61

Skolkovo Institute of Science and Technology

1 citation

Ioni Yulia

42 publications, 468 citations, 10 reviews

h-index: 15

Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences

Top-30

Journals

	1 2 3 4
Science of the Total Environment	Science of the Total Environment, 4, 20% Science of the Total Environment 4 publications, 20%
Ecotoxicology and Environmental Safety	Ecotoxicology and Environmental Safety, 2, 10% Ecotoxicology and Environmental Safety 2 publications, 10%
Toxics	Toxics, 2, 10% Toxics 2 publications, 10%
Chemosphere	Chemosphere, 1, 5% Chemosphere 1 publication, 5%
Environmental Research	Environmental Research, 1, 5% Environmental Research 1 publication, 5%
Environmental Chemistry Letters	Environmental Chemistry Letters, 1, 5% Environmental Chemistry Letters 1 publication, 5%
Journal of Toxicology and Environmental Health - Part B: Critical Reviews	Journal of Toxicology and Environmental Health - Part B: Critical Reviews, 1, 5% Journal of Toxicology and Environmental Health - Part B: Critical Reviews 1 publication, 5%
Microorganisms	Microorganisms, 1, 5% Microorganisms 1 publication, 5%
Water, Air, and Soil Pollution	Water, Air, and Soil Pollution, 1, 5% Water, Air, and Soil Pollution 1 publication, 5%
Russian Chemical Reviews	Russian Chemical Reviews, 1, 5% Russian Chemical Reviews 1 publication, 5%
Indian Journal of Gastroenterology	Indian Journal of Gastroenterology, 1, 5% Indian Journal of Gastroenterology 1 publication, 5%
ACS Nano	ACS Nano, 1, 5% ACS Nano 1 publication, 5%
International Journal of Molecular Medicine	International Journal of Molecular Medicine, 1, 5% International Journal of Molecular Medicine 1 publication, 5%
Journal of Agricultural and Food Chemistry	Journal of Agricultural and Food Chemistry, 1, 5% Journal of Agricultural and Food Chemistry 1 publication, 5%
Communications Earth & Environment	Communications Earth & Environment, 1, 5% Communications Earth & Environment 1 publication, 5%
	1 2 3 4

Publishers

	1 2 3 4 5 6 7 8
Elsevier	Elsevier, 8, 40% Elsevier 8 publications, 40%
Springer Nature	Springer Nature, 4, 20% Springer Nature 4 publications, 20%
MDPI	MDPI, 3, 15% MDPI 3 publications, 15%
American Chemical Society (ACS)	American Chemical Society (ACS), 2, 10% American Chemical Society (ACS) 2 publications, 10%
Taylor & Francis	Taylor & Francis, 1, 5% Taylor & Francis 1 publication, 5%
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii	Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii, 1, 5% Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii 1 publication, 5%
Spandidos Publications	Spandidos Publications, 1, 5% Spandidos Publications 1 publication, 5%
	1 2 3 4 5 6 7 8

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

Metrics

Cite this

GOST |

Cite this

GOST Copy

Li Jiao 李. et al. Co-exposure of polycarbonate microplastics aggravated the toxic effects of imidacloprid on the liver and gut microbiota in mice // Environmental Toxicology and Pharmacology. 2023. Vol. 101. p. 104194.

GOST all authors (up to 50) Copy

Li Jiao 李., Liu J., Zhai L., Lu K. Co-exposure of polycarbonate microplastics aggravated the toxic effects of imidacloprid on the liver and gut microbiota in mice // Environmental Toxicology and Pharmacology. 2023. Vol. 101. p. 104194.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.etap.2023.104194

UR - https://doi.org/10.1016/j.etap.2023.104194

TI - Co-exposure of polycarbonate microplastics aggravated the toxic effects of imidacloprid on the liver and gut microbiota in mice

T2 - Environmental Toxicology and Pharmacology

AU - Li Jiao, 李娇

AU - Liu, Jie

AU - Zhai, Li

AU - Lu, Kun

PY - 2023

DA - 2023/08/01

PB - Elsevier

SP - 104194

VL - 101

PMID - 37348773

SN - 1382-6689

SN - 1872-7077

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2023_Li Jiao,

author = {李娇 Li Jiao and Jie Liu and Li Zhai and Kun Lu},

title = {Co-exposure of polycarbonate microplastics aggravated the toxic effects of imidacloprid on the liver and gut microbiota in mice},

journal = {Environmental Toxicology and Pharmacology},

year = {2023},

volume = {101},

publisher = {Elsevier},

month = {aug},

url = {https://doi.org/10.1016/j.etap.2023.104194},

pages = {104194},

doi = {10.1016/j.etap.2023.104194}

}

Publisher

Elsevier

Journal

Environmental Toxicology and Pharmacology

scimago Q1

wos Q1

SJR

1.064

CiteScore

7.9

Impact factor

4.2

ISSN

13826689 (Print)

18727077