BODIPY-based fluorescent probe for cysteine detection and its applications in food analysis, test strips and biological imaging
Xiaokun Yang
1
,
Jiamin Wang
1
,
Zunlong Zhang
1
,
Bo Zhou
2
,
Xiaolin Du
1
,
Jian Zhang
2
,
Wang Jianhong
1
Publication type: Journal Article
Publication date: 2023-08-01
scimago Q1
wos Q1
SJR: 1.952
CiteScore: 18.3
Impact factor: 9.8
ISSN: 03088146, 18737072
PubMed ID:
36889014
General Medicine
Analytical Chemistry
Food Science
Abstract
Cysteine, as one of semi-essential amino acids, which is absorbed from protein-rich foods and acts considerable role in various physiological processes. Here, we designed and synthesized a BODIPY-based turn-on fluorescent probe BDP-S for detecting Cys. The probe displayed short reaction time (10 min), distinct color response (from blue to pink), large signal noise ratio (3150-fold), high selectivity and sensitivity (LOD = 11.2 nM) toward Cys. Moreover, BDP-S could not only be used for quantitative determination of Cys in food samples, but also be conveniently deposited on the test strips for qualitative detection of Cys. Notably, BDP-S was successfully used for imaging Cys in living cells and in vivo. Consequently, this work provided a hopefully powerful tool for detecting Cys in food samples and complex biological systems.
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Metrics
65
Total citations:
65
Citations from 2024:
46
(70.76%)
The most citing journal
Citations in journal:
9
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GOST
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Yang X. et al. BODIPY-based fluorescent probe for cysteine detection and its applications in food analysis, test strips and biological imaging // Food Chemistry. 2023. Vol. 416. p. 135730.
GOST all authors (up to 50)
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Yang X., Wang J., Zhang Z., Zhou B., Du X., Zhang J., Jianhong W. BODIPY-based fluorescent probe for cysteine detection and its applications in food analysis, test strips and biological imaging // Food Chemistry. 2023. Vol. 416. p. 135730.
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RIS
Copy
TY - JOUR
DO - 10.1016/j.foodchem.2023.135730
UR - https://doi.org/10.1016/j.foodchem.2023.135730
TI - BODIPY-based fluorescent probe for cysteine detection and its applications in food analysis, test strips and biological imaging
T2 - Food Chemistry
AU - Yang, Xiaokun
AU - Wang, Jiamin
AU - Zhang, Zunlong
AU - Zhou, Bo
AU - Du, Xiaolin
AU - Zhang, Jian
AU - Jianhong, Wang
PY - 2023
DA - 2023/08/01
PB - Elsevier
SP - 135730
VL - 416
PMID - 36889014
SN - 0308-8146
SN - 1873-7072
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_Yang,
author = {Xiaokun Yang and Jiamin Wang and Zunlong Zhang and Bo Zhou and Xiaolin Du and Jian Zhang and Wang Jianhong},
title = {BODIPY-based fluorescent probe for cysteine detection and its applications in food analysis, test strips and biological imaging},
journal = {Food Chemistry},
year = {2023},
volume = {416},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.foodchem.2023.135730},
pages = {135730},
doi = {10.1016/j.foodchem.2023.135730}
}
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