Journal of Drug Delivery Science and Technology

, volume 95 , pages 105524

Bioceramic materials in bone-implantable drug delivery systems: A review

Amit Nayak ^{1, 2}

Mala Maity ³

Harekrushna Barik ⁴

Sidhartha Sankar Behera ⁵

Amal Kumar Dhara ⁶

Md Saquib Hasnain ⁴

Hide authors affiliations Show authors affiliations: 6 affiliations

Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan (Deemed to be University), Bhubaneswar, 751003, Odisha, India |

Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, 751003, Odisha, India |

Department of Pharmacy, Anand College of Education, Kabilpur, Debra, Paschim Medinipur 721126, West Bengal, India |

⁴

Department of Pharmacy, Palamau Institute of Pharmacy, Chianki, Daltonganj, 822102, Jharkhand, India |

⁵

Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Odisha University of Agriculture and Technology, Bhubaneswar, 751003, Odisha, India |

⁶

Department of Pharmacy, Contai Polytechnic, Darua, Contai, 721401, West Bengal, India |

Publication type: Journal Article

Publication date: 2024-05-01

Elsevier

Journal of Drug Delivery Science and Technology

scimago Q1

wos Q1

SJR: 0.817

CiteScore: 8.3

Impact factor: 4.9

ISSN: 17732247, 25888943, 11571489

DOI: 10.1016/j.jddst.2024.105524

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Pharmaceutical Science

Abstract

Since long, the applications of bioceramics in bone-implantable drug delivery has revealed a significant impact due to some favorable merits, such as excellent biocompatibility, good bioactivity, nonimmunogenicity, osteoconductivity, bone resorbability and controllable porous microstructure. To treat different disorders and diseases, such as fracture, osteoporosis, osteoarthritis, osteomyelitis, osseous cancer, etc., various drug releasing bone-implants composed of bioceramics have widely been investigated. During the last few decades, a large number of drugs (like antibiotics, anticancer agents, anti-inflammatory agents, proteins and peptides, growth factors, etc.) have been investigated for the controlled release by bone-implants made up of bioceramics. Amongst various bioceramics, calcium sulfate, calcium phosphates and bioactive glasses are being mostly used in the formula of drug releasing bone-implants. This review article describes about different bioceramic materials, which are being used to formulate drug releasing bone-implants to treat different bone diseases and disorders.

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GOST |

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GOST Copy

Nayak A. et al. Bioceramic materials in bone-implantable drug delivery systems: A review // Journal of Drug Delivery Science and Technology. 2024. Vol. 95. p. 105524.

GOST all authors (up to 50) Copy

Nayak A., Maity M., Barik H., Behera S. S., Dhara A. K., Hasnain M. S. Bioceramic materials in bone-implantable drug delivery systems: A review // Journal of Drug Delivery Science and Technology. 2024. Vol. 95. p. 105524.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.jddst.2024.105524

UR - https://linkinghub.elsevier.com/retrieve/pii/S1773224724001928

TI - Bioceramic materials in bone-implantable drug delivery systems: A review

T2 - Journal of Drug Delivery Science and Technology

AU - Nayak, Amit

AU - Maity, Mala

AU - Barik, Harekrushna

AU - Behera, Sidhartha Sankar

AU - Dhara, Amal Kumar

AU - Hasnain, Md Saquib

PY - 2024

DA - 2024/05/01

PB - Elsevier

SP - 105524

VL - 95

SN - 1773-2247

SN - 2588-8943

SN - 1157-1489

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2024_Nayak,

author = {Amit Nayak and Mala Maity and Harekrushna Barik and Sidhartha Sankar Behera and Amal Kumar Dhara and Md Saquib Hasnain},

title = {Bioceramic materials in bone-implantable drug delivery systems: A review},

journal = {Journal of Drug Delivery Science and Technology},

year = {2024},

volume = {95},

publisher = {Elsevier},

month = {may},

url = {https://linkinghub.elsevier.com/retrieve/pii/S1773224724001928},

pages = {105524},

doi = {10.1016/j.jddst.2024.105524}

}

Publisher

Elsevier

Journal

Journal of Drug Delivery Science and Technology

scimago Q1

wos Q1

SJR

0.817

CiteScore

8.3

Impact factor

4.9

ISSN

17732247 (Print)

25888943 (Electronic)

11571489 (Print)