The role of pyocyanin in Pseudomonas aeruginosa infection
Publication type: Journal Article
Publication date: 2004-12-01
scimago Q1
wos Q1
SJR: 3.577
CiteScore: 21.9
Impact factor: 13.8
ISSN: 14714914, 1471499X
PubMed ID:
15567330
Molecular Biology
Molecular Medicine
Abstract
Pyocyanin (PCN) is a blue redox-active secondary metabolite that is produced by Pseudomonas aeruginosa. PCN is readily recovered in large quantities in sputum from patients with cystic fibrosis who are infected by P. aeruginosa. Despite in vitro studies demonstrating that PCN interferes with multiple cellular functions, its importance during clinical infection is uncertain. This is partially caused by the difficulty in defining the contribution of PCN among the numerous virulence factors produced by P. aeruginosa during infection. In addition, few cellular pathways that are affected by PCN are known. This review briefly highlights recent advances that might clarify the role of PCN in P. aeruginosa pathogenesis.
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Metrics
606
Total citations:
606
Citations from 2025:
48
(7.93%)
Cite this
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MLA
Cite this
GOST
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Lau G. W. et al. The role of pyocyanin in Pseudomonas aeruginosa infection // Trends in Molecular Medicine. 2004. Vol. 10. No. 12. pp. 599-606.
GOST all authors (up to 50)
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Lau G. W., Hassett D. R., Ran H., Kong F. The role of pyocyanin in Pseudomonas aeruginosa infection // Trends in Molecular Medicine. 2004. Vol. 10. No. 12. pp. 599-606.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.molmed.2004.10.002
UR - https://doi.org/10.1016/j.molmed.2004.10.002
TI - The role of pyocyanin in Pseudomonas aeruginosa infection
T2 - Trends in Molecular Medicine
AU - Lau, Gee W.
AU - Hassett, Daniel R
AU - Ran, Huimin
AU - Kong, Fansheng
PY - 2004
DA - 2004/12/01
PB - Elsevier
SP - 599-606
IS - 12
VL - 10
PMID - 15567330
SN - 1471-4914
SN - 1471-499X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2004_Lau,
author = {Gee W. Lau and Daniel R Hassett and Huimin Ran and Fansheng Kong},
title = {The role of pyocyanin in Pseudomonas aeruginosa infection},
journal = {Trends in Molecular Medicine},
year = {2004},
volume = {10},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/j.molmed.2004.10.002},
number = {12},
pages = {599--606},
doi = {10.1016/j.molmed.2004.10.002}
}
Cite this
MLA
Copy
Lau, Gee W., et al. “The role of pyocyanin in Pseudomonas aeruginosa infection.” Trends in Molecular Medicine, vol. 10, no. 12, Dec. 2004, pp. 599-606. https://doi.org/10.1016/j.molmed.2004.10.002.