Polymeric nanoparticles for targeted drug delivery system for cancer therapy
Publication type: Journal Article
Publication date: 2016-03-01
SJR: —
CiteScore: —
Impact factor: —
ISSN: 09284931, 18730191
PubMed ID:
26706565
Bioengineering
Biomaterials
Mechanics of Materials
Abstract
A targeted delivery system based on the polymeric nanoparticles as a drug carrier represents a marvelous avenue for cancer therapy. The pivotal characteristics of this system include biodegradability, biocompatibility, non-toxicity, prolonged circulation and a wide payload spectrum of a therapeutic agent. Other outstanding features are their distinctive size and shape properties for tissue penetration via an active and passive targeting, specific cellular/subcellular trafficking pathways and facile control of cargo release by sophisticated material engineering. In this review, the current implications of encapsulation of anticancer agents within polyhydroxyalkanoates, poly-(lactic-co-glycolic acid) and cyclodextrin based nanoparticles to precisely target the tumor site, i.e., cell, tissue and organ are highlighted. Furthermore, the promising perspectives in this emerging field are discussed.
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Metrics
601
Total citations:
601
Citations from 2025:
61
(10.15%)
Cite this
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GOST
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Masood F. Polymeric nanoparticles for targeted drug delivery system for cancer therapy // Materials Science and Engineering C. 2016. Vol. 60. pp. 569-578.
GOST all authors (up to 50)
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Masood F. Polymeric nanoparticles for targeted drug delivery system for cancer therapy // Materials Science and Engineering C. 2016. Vol. 60. pp. 569-578.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.msec.2015.11.067
UR - https://linkinghub.elsevier.com/retrieve/pii/S0928493115305981
TI - Polymeric nanoparticles for targeted drug delivery system for cancer therapy
T2 - Materials Science and Engineering C
AU - Masood, Farha
PY - 2016
DA - 2016/03/01
PB - Elsevier
SP - 569-578
VL - 60
PMID - 26706565
SN - 0928-4931
SN - 1873-0191
ER -
Cite this
BibTex (up to 50 authors)
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@article{2016_Masood,
author = {Farha Masood},
title = {Polymeric nanoparticles for targeted drug delivery system for cancer therapy},
journal = {Materials Science and Engineering C},
year = {2016},
volume = {60},
publisher = {Elsevier},
month = {mar},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0928493115305981},
pages = {569--578},
doi = {10.1016/j.msec.2015.11.067}
}