Materials Today Chemistry, volume 29, pages 101445
Photocontrolled release of nitric oxide for precise management of NO concentration in a solution
Publication type: Journal Article
Publication date: 2023-04-01
Journal:
Materials Today Chemistry
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 7.3
ISSN: 24685194
Materials Chemistry
Electronic, Optical and Magnetic Materials
Catalysis
Colloid and Surface Chemistry
Polymers and Plastics
Biomaterials
Abstract
Nitric oxide (NO) is a unique biochemical mediator involved in the regulation of vital processes. Its short half-life and local action impede direct application in medical practice. Light-controllable NO releasers are promising for the development of smart therapies. Here, we present novel aza-BODIPY derivative containing N-nitroso moiety, which shows efficient and reversible release of NO under red light. Using this molecule, we demonstrate a system for precise management of NO concentration in aqueous solution in vitro using the feedback loop with optical control. Our results could serve as the basis for the development of novel therapeutic methods.
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Zhermolenko E. et al. Photocontrolled release of nitric oxide for precise management of NO concentration in a solution // Materials Today Chemistry. 2023. Vol. 29. p. 101445.
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Zhermolenko E., Karogodina T. Yu., Vorobev A. Yu., Panfilov M. A., Moskalensky A. E. Photocontrolled release of nitric oxide for precise management of NO concentration in a solution // Materials Today Chemistry. 2023. Vol. 29. p. 101445.
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TY - JOUR
DO - 10.1016/j.mtchem.2023.101445
UR - https://doi.org/10.1016%2Fj.mtchem.2023.101445
TI - Photocontrolled release of nitric oxide for precise management of NO concentration in a solution
T2 - Materials Today Chemistry
AU - Zhermolenko, E.O.
AU - Karogodina, T Yu
AU - Vorobev, Aleksey Yu
AU - Panfilov, Mikhail A.
AU - Moskalensky, Alexander E.
PY - 2023
DA - 2023/04/01 00:00:00
PB - Elsevier
SP - 101445
VL - 29
SN - 2468-5194
ER -
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@article{2023_Zhermolenko,
author = {E.O. Zhermolenko and T Yu Karogodina and Aleksey Yu Vorobev and Mikhail A. Panfilov and Alexander E. Moskalensky},
title = {Photocontrolled release of nitric oxide for precise management of NO concentration in a solution},
journal = {Materials Today Chemistry},
year = {2023},
volume = {29},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016%2Fj.mtchem.2023.101445},
pages = {101445},
doi = {10.1016/j.mtchem.2023.101445}
}
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