Mild and direct conversion of esters to morpholine amides using diisobutyl(morpholino)aluminum: application to efficient one-pot synthesis of ketones and aldehydes from esters
Publication type: Journal Article
Publication date: 2014-07-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Morpholine amide intermediates, which are easily prepared by aminolysis of various esters with diisobutyl(morpholino)aluminum, react with organolithium and reducing agents (DIBALH or LDBMA) without isolation of the aminolysis intermediates to give ketones in 83–95% yields and aldehydes quantitatively.
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28
Total citations:
28
Citations from 2024:
10
(35.71%)
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GOST
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Jeon A. R. et al. Mild and direct conversion of esters to morpholine amides using diisobutyl(morpholino)aluminum: application to efficient one-pot synthesis of ketones and aldehydes from esters // Tetrahedron. 2014. Vol. 70. No. 29. pp. 4420-4424.
GOST all authors (up to 50)
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Jeon A. R., Kim M. E., Park J. K., Shin W. K., An D. K. Mild and direct conversion of esters to morpholine amides using diisobutyl(morpholino)aluminum: application to efficient one-pot synthesis of ketones and aldehydes from esters // Tetrahedron. 2014. Vol. 70. No. 29. pp. 4420-4424.
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RIS
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TY - JOUR
DO - 10.1016/j.tet.2014.03.045
UR - https://doi.org/10.1016/j.tet.2014.03.045
TI - Mild and direct conversion of esters to morpholine amides using diisobutyl(morpholino)aluminum: application to efficient one-pot synthesis of ketones and aldehydes from esters
T2 - Tetrahedron
AU - Jeon, Ah Ram
AU - Kim, Min Eai
AU - Park, Jae Kyo
AU - Shin, Won Kyu
AU - An, Duk Keun
PY - 2014
DA - 2014/07/01
PB - Elsevier
SP - 4420-4424
IS - 29
VL - 70
SN - 0040-4020
SN - 1464-5416
ER -
Cite this
BibTex (up to 50 authors)
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@article{2014_Jeon,
author = {Ah Ram Jeon and Min Eai Kim and Jae Kyo Park and Won Kyu Shin and Duk Keun An},
title = {Mild and direct conversion of esters to morpholine amides using diisobutyl(morpholino)aluminum: application to efficient one-pot synthesis of ketones and aldehydes from esters},
journal = {Tetrahedron},
year = {2014},
volume = {70},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.tet.2014.03.045},
number = {29},
pages = {4420--4424},
doi = {10.1016/j.tet.2014.03.045}
}
Cite this
MLA
Copy
Jeon, Ah Ram, et al. “Mild and direct conversion of esters to morpholine amides using diisobutyl(morpholino)aluminum: application to efficient one-pot synthesis of ketones and aldehydes from esters.” Tetrahedron, vol. 70, no. 29, Jul. 2014, pp. 4420-4424. https://doi.org/10.1016/j.tet.2014.03.045.