Synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxides as valuable synthons for anticancer molecules
Natalia B Chernysheva
1
,
Anna Maksimenko
1
,
Victor P. Kislyi
1
,
Yuri A. Strelenko
1
,
Marina Semenova
3
,
Victor Semenov
1
Publication type: Journal Article
Publication date: 2017-11-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
The convenient regioselective scalable synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxides was developed based on a condensation of simple starting materials (arylbenzaldehydes, arylnitromethanes, and ethoxycarbonylmethylpyridinium bromide) under mild conditions. The obtained synthons can be applied for the synthesis of 3,4-diarylisoxazole derivatives capable of suppressing malignant growth.
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Metrics
22
Total citations:
22
Citations from 2025:
2
(9.09%)
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GOST
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Chernysheva N. B. et al. Synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxides as valuable synthons for anticancer molecules // Tetrahedron. 2017. Vol. 73. No. 48. pp. 6728-6735.
GOST all authors (up to 50)
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Chernysheva N. B., Maksimenko A., Andreyanov F. A., Kislyi V. P., Strelenko Y. A., Khrustalev V. N., Semenova M., Semenov V. Synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxides as valuable synthons for anticancer molecules // Tetrahedron. 2017. Vol. 73. No. 48. pp. 6728-6735.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.tet.2017.10.016
UR - https://doi.org/10.1016/j.tet.2017.10.016
TI - Synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxides as valuable synthons for anticancer molecules
T2 - Tetrahedron
AU - Chernysheva, Natalia B
AU - Maksimenko, Anna
AU - Andreyanov, Fedor A
AU - Kislyi, Victor P.
AU - Strelenko, Yuri A.
AU - Khrustalev, Victor N.
AU - Semenova, Marina
AU - Semenov, Victor
PY - 2017
DA - 2017/11/01
PB - Elsevier
SP - 6728-6735
IS - 48
VL - 73
SN - 0040-4020
SN - 1464-5416
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2017_Chernysheva,
author = {Natalia B Chernysheva and Anna Maksimenko and Fedor A Andreyanov and Victor P. Kislyi and Yuri A. Strelenko and Victor N. Khrustalev and Marina Semenova and Victor Semenov},
title = {Synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxides as valuable synthons for anticancer molecules},
journal = {Tetrahedron},
year = {2017},
volume = {73},
publisher = {Elsevier},
month = {nov},
url = {https://doi.org/10.1016/j.tet.2017.10.016},
number = {48},
pages = {6728--6735},
doi = {10.1016/j.tet.2017.10.016}
}
Cite this
MLA
Copy
Chernysheva, Natalia B., et al. “Synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxides as valuable synthons for anticancer molecules.” Tetrahedron, vol. 73, no. 48, Nov. 2017, pp. 6728-6735. https://doi.org/10.1016/j.tet.2017.10.016.
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