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volume 2 issue 6 pages 100446

A critical review of palladium organometallic anticancer agents

Publication typeJournal Article
Publication date2021-06-01
scimago Q1
wos Q1
SJR2.098
CiteScore12.0
Impact factor7.3
ISSN26663864
General Chemistry
General Physics and Astronomy
General Materials Science
General Energy
General Engineering
Abstract
With the aim of overcoming the well-known limitations of platinum-based antineoplastic drugs, recent efforts have focused on the development of new anticancer agents containing metals other than platinum. Among these agents, organopalladium compounds have received significant recent attention due to their generally high stability under physiological conditions. A significant number of these compounds have shown promising in vitro and in vivo antiproliferative activity toward several cisplatin-sensitive and cisplatin-resistant tumors and have sometimes exhibited a different mechanism of action compared to platinum-based drugs. In this review, recent advances in the field of organopalladium compounds as potential anticancer agents are discussed. Organopalladium compounds have received significant recent attention due to their generally high stability under physiological conditions. This review by Scattolin et al. discusses several compounds that have shown promising in vitro and in vivo antiproliferative activity toward several tumors and have sometimes exhibited a different mechanism of action compared to platinum-based drugs.
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GOST |
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GOST Copy
Scattolin T. et al. A critical review of palladium organometallic anticancer agents // Cell Reports Physical Science. 2021. Vol. 2. No. 6. p. 100446.
GOST all authors (up to 50) Copy
Scattolin T., Voloshkin V. A., Visentin F., Nolan S. P. A critical review of palladium organometallic anticancer agents // Cell Reports Physical Science. 2021. Vol. 2. No. 6. p. 100446.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.xcrp.2021.100446
UR - https://doi.org/10.1016/j.xcrp.2021.100446
TI - A critical review of palladium organometallic anticancer agents
T2 - Cell Reports Physical Science
AU - Scattolin, Thomas
AU - Voloshkin, Vladislav A.
AU - Visentin, Fabiano
AU - Nolan, Steven P.
PY - 2021
DA - 2021/06/01
PB - Elsevier
SP - 100446
IS - 6
VL - 2
SN - 2666-3864
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Scattolin,
author = {Thomas Scattolin and Vladislav A. Voloshkin and Fabiano Visentin and Steven P. Nolan},
title = {A critical review of palladium organometallic anticancer agents},
journal = {Cell Reports Physical Science},
year = {2021},
volume = {2},
publisher = {Elsevier},
month = {jun},
url = {https://doi.org/10.1016/j.xcrp.2021.100446},
number = {6},
pages = {100446},
doi = {10.1016/j.xcrp.2021.100446}
}
MLA
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MLA Copy
Scattolin, Thomas, et al. “A critical review of palladium organometallic anticancer agents.” Cell Reports Physical Science, vol. 2, no. 6, Jun. 2021, p. 100446. https://doi.org/10.1016/j.xcrp.2021.100446.