volume 27 issue 6 pages 392-397

Reference genes selection for real-time quantitative PCR analysis in mouse germinal vesicle oocytes

Publication typeJournal Article
Publication date2019-09-23
scimago Q4
wos Q4
SJR0.417
CiteScore2.6
Impact factor1.4
ISSN09671994, 14698730
Cell Biology
Developmental Biology
Abstract
Summary

Reference gene selection in mouse oocytes is an important task required to perform further adequate analysis of target gene expression levels. In the current work we have analyzed expression stability of the seven most commonly used reference genes (Actb, Eef1e1, Gapdh, H2afz, Ppia, Rpl4 and Ubc) in mouse oocytes at the germinal vesicle (GV) stage. We have performed analysis of expression stability of the above-mentioned reference genes with the three most commonly used software tools: geNorm, BestKeeper and NormFinder. Taking into account the results obtained from all of these programmes Gapdh, Rpl4 and H2afz seem to be suitable candidate reference genes in GV oocytes of mouse.

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GOST Copy
Filatov M. A. et al. Reference genes selection for real-time quantitative PCR analysis in mouse germinal vesicle oocytes // Zygote. 2019. Vol. 27. No. 6. pp. 392-397.
GOST all authors (up to 50) Copy
Filatov M. A., Nikishin D. A., Khramova Y. V., Semenova M. L. Reference genes selection for real-time quantitative PCR analysis in mouse germinal vesicle oocytes // Zygote. 2019. Vol. 27. No. 6. pp. 392-397.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1017/S0967199419000492
UR - https://doi.org/10.1017/S0967199419000492
TI - Reference genes selection for real-time quantitative PCR analysis in mouse germinal vesicle oocytes
T2 - Zygote
AU - Filatov, Maxim A
AU - Nikishin, D A
AU - Khramova, Y V
AU - Semenova, M L
PY - 2019
DA - 2019/09/23
PB - Cambridge University Press
SP - 392-397
IS - 6
VL - 27
PMID - 31544726
SN - 0967-1994
SN - 1469-8730
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2019_Filatov,
author = {Maxim A Filatov and D A Nikishin and Y V Khramova and M L Semenova},
title = {Reference genes selection for real-time quantitative PCR analysis in mouse germinal vesicle oocytes},
journal = {Zygote},
year = {2019},
volume = {27},
publisher = {Cambridge University Press},
month = {sep},
url = {https://doi.org/10.1017/S0967199419000492},
number = {6},
pages = {392--397},
doi = {10.1017/S0967199419000492}
}
MLA
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MLA Copy
Filatov, Maxim A., et al. “Reference genes selection for real-time quantitative PCR analysis in mouse germinal vesicle oocytes.” Zygote, vol. 27, no. 6, Sep. 2019, pp. 392-397. https://doi.org/10.1017/S0967199419000492.