Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine
Jeffrey T Kohrt
1
,
Peter H Dorff
1
,
Michael Burns
2
,
Chewah Lee
2
,
Steven V Oneil
2
,
Robert J Maguire
2
,
Rajesh Kumar
2
,
Melissa Wagenaar
2
,
Loren Price
1
,
Manjinder Lall
1
1
Medicine Design, Pfizer Inc., 445 Eastern Point Road, Groton, Connecticut 06340, United States
|
2
Chemical Research and Development, Pfizer Inc., 445 Eastern Point Road, Groton, Connecticut 06340, United States
|
Publication type: Journal Article
Publication date: 2021-04-14
scimago Q1
wos Q1
SJR: 0.865
CiteScore: 5.4
Impact factor: 3.5
ISSN: 10836160, 1520586X
Organic Chemistry
Physical and Theoretical Chemistry
Abstract
Spirocyclic ring systems are useful intermediates in the design and synthesis of medicinally active agents and commonly found as cores in natural products. Recently, syntheses of a key intermediate...
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Metrics
14
Total citations:
14
Citations from 2024:
3
(21%)
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GOST
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Kohrt J. T. et al. Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine // Organic Process Research and Development. 2021. Vol. 26. No. 3. pp. 616-623.
GOST all authors (up to 50)
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Kohrt J. T., Dorff P. H., Burns M., Lee C., Oneil S. V., Maguire R. J., Kumar R., Wagenaar M., Price L., Lall M. Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine // Organic Process Research and Development. 2021. Vol. 26. No. 3. pp. 616-623.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.oprd.1c00075
UR - https://doi.org/10.1021/acs.oprd.1c00075
TI - Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine
T2 - Organic Process Research and Development
AU - Kohrt, Jeffrey T
AU - Dorff, Peter H
AU - Burns, Michael
AU - Lee, Chewah
AU - Oneil, Steven V
AU - Maguire, Robert J
AU - Kumar, Rajesh
AU - Wagenaar, Melissa
AU - Price, Loren
AU - Lall, Manjinder
PY - 2021
DA - 2021/04/14
PB - American Chemical Society (ACS)
SP - 616-623
IS - 3
VL - 26
SN - 1083-6160
SN - 1520-586X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Kohrt,
author = {Jeffrey T Kohrt and Peter H Dorff and Michael Burns and Chewah Lee and Steven V Oneil and Robert J Maguire and Rajesh Kumar and Melissa Wagenaar and Loren Price and Manjinder Lall},
title = {Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine},
journal = {Organic Process Research and Development},
year = {2021},
volume = {26},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/acs.oprd.1c00075},
number = {3},
pages = {616--623},
doi = {10.1021/acs.oprd.1c00075}
}
Cite this
MLA
Copy
Kohrt, Jeffrey T., et al. “Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine.” Organic Process Research and Development, vol. 26, no. 3, Apr. 2021, pp. 616-623. https://doi.org/10.1021/acs.oprd.1c00075.