Chemistry of Materials, volume 14, issue 5, pages 2113-2119

Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots

Publication typeJournal Article
Publication date2002-04-23
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor8.6
ISSN08974756, 15205002
Materials Chemistry
General Chemistry
General Chemical Engineering
Abstract
Water-soluble, highly fluorescent, silanized semiconductor nanocrystals with different surface charges were synthesized. To covalently attach the nanocrystals to biological macromolecules with a variety of mild coupling chemistries, the outermost siloxane shells were derivatized with thiol, amino, or carboxyl functional groups. Single- or double-stranded DNA was coupled to the nanocrystal surfaces by using commercially available bifunctional cross-linker. Conjugation had little effect on the optical properties of the nanocrystals, and the resulting conjugates were more stable than previously reported systems. By using the strategies developed in this study, most biomolecules can be covalently coupled to semiconductor nanocrystals. These nanocrystal-DNA conjugates promise to be a versatile tool for fluorescence imaging and probing of biological systems.

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Parak W. J. et al. Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots // Chemistry of Materials. 2002. Vol. 14. No. 5. pp. 2113-2119.
GOST all authors (up to 50) Copy
Parak W. J., Gerion D., Zanchet D., Woerz A. S., Pellegrino T., Micheel C., Williams S. C., Seitz M., Bruehl R. E., Bryant Z., Bustamante C., Bertozzi C. R., Alivisatos A. P. Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots // Chemistry of Materials. 2002. Vol. 14. No. 5. pp. 2113-2119.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/cm0107878
UR - https://doi.org/10.1021/cm0107878
TI - Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots
T2 - Chemistry of Materials
AU - Gerion, Daniele
AU - Zanchet, Daniela
AU - Woerz, Anke S
AU - Micheel, Christine
AU - Williams, Shara C
AU - Seitz, Markus
AU - Bruehl, Richard E.
AU - Bryant, Zev
AU - Bustamante, Carlos
AU - Bertozzi, Carolyn R.
AU - Parak, Wolfgang J.
AU - Pellegrino, Teresa
AU - Alivisatos, A. Paul
PY - 2002
DA - 2002/04/23 00:00:00
PB - American Chemical Society (ACS)
SP - 2113-2119
IS - 5
VL - 14
SN - 0897-4756
SN - 1520-5002
ER -
BibTex |
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BibTex Copy
@article{2002_Parak,
author = {Daniele Gerion and Daniela Zanchet and Anke S Woerz and Christine Micheel and Shara C Williams and Markus Seitz and Richard E. Bruehl and Zev Bryant and Carlos Bustamante and Carolyn R. Bertozzi and Wolfgang J. Parak and Teresa Pellegrino and A. Paul Alivisatos},
title = {Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots},
journal = {Chemistry of Materials},
year = {2002},
volume = {14},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/cm0107878},
number = {5},
pages = {2113--2119},
doi = {10.1021/cm0107878}
}
MLA
Cite this
MLA Copy
Parak, Wolfgang J., et al. “Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots.” Chemistry of Materials, vol. 14, no. 5, Apr. 2002, pp. 2113-2119. https://doi.org/10.1021/cm0107878.
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