volume 135 issue 45 pages 16841-16844

A palladium-catalyzed carbonylation approach to acid chloride synthesis.

Publication typeJournal Article
Publication date2013-10-29
scimago Q1
wos Q1
SJR5.554
CiteScore22.5
Impact factor15.6
ISSN00027863, 15205126
PubMed ID:  24144068
General Chemistry
Catalysis
Biochemistry
Colloid and Surface Chemistry
Abstract
We describe a new approach to acid chloride synthesis via the palladium-catalyzed carbonylation of aryl iodides. The combination of sterically encumbered phosphines (P(t)Bu3) and CO coordination has been found to facilitate the rapid carbonylation of aryl iodides into acid chlorides via reductive elimination from ((t)Bu3P)(CO)Pd(COAr)Cl. The formation of acid chlorides can also be exploited to perform traditional aminocarbonylation reactions under exceptionally mild conditions (ambient temperature and pressure), and with a range of weakly nucleophilic substrates.
Found 
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GOST |
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GOST Copy
Quesnel J. S., Arndtsen B. A. A palladium-catalyzed carbonylation approach to acid chloride synthesis. // Journal of the American Chemical Society. 2013. Vol. 135. No. 45. pp. 16841-16844.
GOST all authors (up to 50) Copy
Quesnel J. S., Arndtsen B. A. A palladium-catalyzed carbonylation approach to acid chloride synthesis. // Journal of the American Chemical Society. 2013. Vol. 135. No. 45. pp. 16841-16844.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/ja4098093
UR - https://doi.org/10.1021/ja4098093
TI - A palladium-catalyzed carbonylation approach to acid chloride synthesis.
T2 - Journal of the American Chemical Society
AU - Quesnel, Jeffrey S
AU - Arndtsen, Bruce A
PY - 2013
DA - 2013/10/29
PB - American Chemical Society (ACS)
SP - 16841-16844
IS - 45
VL - 135
PMID - 24144068
SN - 0002-7863
SN - 1520-5126
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2013_Quesnel,
author = {Jeffrey S Quesnel and Bruce A Arndtsen},
title = {A palladium-catalyzed carbonylation approach to acid chloride synthesis.},
journal = {Journal of the American Chemical Society},
year = {2013},
volume = {135},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/ja4098093},
number = {45},
pages = {16841--16844},
doi = {10.1021/ja4098093}
}
MLA
Cite this
MLA Copy
Quesnel, Jeffrey S., and Bruce A Arndtsen. “A palladium-catalyzed carbonylation approach to acid chloride synthesis..” Journal of the American Chemical Society, vol. 135, no. 45, Oct. 2013, pp. 16841-16844. https://doi.org/10.1021/ja4098093.