Journal of Medicinal Chemistry, volume 58, issue 7, pages 2895-2940
Organic Carbamates in Drug Design and Medicinal Chemistry
Arun K Ghosh
1
,
Margherita Brindisi
1
Publication type: Journal Article
Publication date: 2015-01-07
Journal:
Journal of Medicinal Chemistry
scimago Q1
SJR: 1.986
CiteScore: 12.8
Impact factor: 6.8
ISSN: 00222623, 15204804
PubMed ID:
25565044
Drug Discovery
Molecular Medicine
Abstract
The carbamate group is a key structural motif in many approved drugs and prodrugs. There is an increasing use of carbamates in medicinal chemistry and many derivatives are specifically designed to make drug-target interactions through their carbamate moiety. In this Perspective, we present properties and stabilities of carbamates, reagents and chemical methodologies for the synthesis of carbamates, and recent applications of carbamates in drug design and medicinal chemistry.
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GOST
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Ghosh A. K., Brindisi M. Organic Carbamates in Drug Design and Medicinal Chemistry // Journal of Medicinal Chemistry. 2015. Vol. 58. No. 7. pp. 2895-2940.
GOST all authors (up to 50)
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Ghosh A. K., Brindisi M. Organic Carbamates in Drug Design and Medicinal Chemistry // Journal of Medicinal Chemistry. 2015. Vol. 58. No. 7. pp. 2895-2940.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/jm501371s
UR - https://doi.org/10.1021/jm501371s
TI - Organic Carbamates in Drug Design and Medicinal Chemistry
T2 - Journal of Medicinal Chemistry
AU - Ghosh, Arun K
AU - Brindisi, Margherita
PY - 2015
DA - 2015/01/07
PB - American Chemical Society (ACS)
SP - 2895-2940
IS - 7
VL - 58
PMID - 25565044
SN - 0022-2623
SN - 1520-4804
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2015_Ghosh,
author = {Arun K Ghosh and Margherita Brindisi},
title = {Organic Carbamates in Drug Design and Medicinal Chemistry},
journal = {Journal of Medicinal Chemistry},
year = {2015},
volume = {58},
publisher = {American Chemical Society (ACS)},
month = {jan},
url = {https://doi.org/10.1021/jm501371s},
number = {7},
pages = {2895--2940},
doi = {10.1021/jm501371s}
}
Cite this
MLA
Copy
Ghosh, Arun K., and Margherita Brindisi. “Organic Carbamates in Drug Design and Medicinal Chemistry.” Journal of Medicinal Chemistry, vol. 58, no. 7, Jan. 2015, pp. 2895-2940. https://doi.org/10.1021/jm501371s.
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Publisher
Journal
scimago Q1
SJR
1.986
CiteScore
12.8
Impact factor
6.8
ISSN
00222623
(Print)
15204804
(Electronic)