Characterization of the Congeners in the Lantibiotic NAI-107 Complex
Тип публикации: Journal Article
Дата публикации: 2014-01-14
SCImago Q1
WOS Q2
БС1
SJR: 0.585
CiteScore: 6.3
Impact factor: 3.7
ISSN: 01633864, 15206025
PubMed ID:
24422756
Organic Chemistry
Drug Discovery
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Краткое описание
NAI-107, a lantibiotic produced by Microbispora sp. 107891, shows potent activity against multi-drug-resistant bacterial pathogens. It is produced as a complex of related molecules, which is unusual for ribosomally synthesized peptides. Here we describe the identification, characterization, and antibacterial activity of the congeners produced by Microbispora sp. 107891 and by the related Microbispora corallina NRRL 30420. These molecules differ by the presence of two, one, or zero hydroxyl groups at Pro-14, by the presence of a chlorine at Trp-4, and/or by the presence of a sulfoxide on the thioether of the first lanthionine.
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MLA
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ГОСТ
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Maffioli S. et al. Characterization of the Congeners in the Lantibiotic NAI-107 Complex // Journal of Natural Products. 2014. Vol. 77. No. 1. pp. 79-84.
ГОСТ со всеми авторами (до 50)
Скопировать
Maffioli S., Iorio M., Sosio M., Monciardini P., Gaspari E., Donadio S. Characterization of the Congeners in the Lantibiotic NAI-107 Complex // Journal of Natural Products. 2014. Vol. 77. No. 1. pp. 79-84.
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RIS
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TY - JOUR
DO - 10.1021/np400702t
UR - https://doi.org/10.1021/np400702t
TI - Characterization of the Congeners in the Lantibiotic NAI-107 Complex
T2 - Journal of Natural Products
AU - Maffioli, S.
AU - Iorio, Marianna
AU - Sosio, Margherita
AU - Monciardini, Paolo
AU - Gaspari, Eleonora
AU - Donadio, Stefano
PY - 2014
DA - 2014/01/14
PB - American Chemical Society (ACS)
SP - 79-84
IS - 1
VL - 77
PMID - 24422756
SN - 0163-3864
SN - 1520-6025
ER -
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BibTex (до 50 авторов)
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@article{2014_Maffioli,
author = {S. Maffioli and Marianna Iorio and Margherita Sosio and Paolo Monciardini and Eleonora Gaspari and Stefano Donadio},
title = {Characterization of the Congeners in the Lantibiotic NAI-107 Complex},
journal = {Journal of Natural Products},
year = {2014},
volume = {77},
publisher = {American Chemical Society (ACS)},
month = {jan},
url = {https://doi.org/10.1021/np400702t},
number = {1},
pages = {79--84},
doi = {10.1021/np400702t}
}
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MLA
Скопировать
Maffioli, S., et al. “Characterization of the Congeners in the Lantibiotic NAI-107 Complex.” Journal of Natural Products, vol. 77, no. 1, Jan. 2014, pp. 79-84. https://doi.org/10.1021/np400702t.
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