Ethyl 2-Chlorooxazole-4-carboxylate: A Versatile Intermediate for the Synthesis of Substituted Oxazoles
1
Neurogen Corporation, 35 Northeast Industrial Road, Branford, Connecticut 06405
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Publication type: Journal Article
Publication date: 2002-07-23
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
12182585
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
[reaction: see text] By using a sequence of regiocontrolled halogenation and palladium-catalyzed coupling reactions, the synthesis of variously substituted oxazoles from ethyl 2-chlorooxazole-4-carboxylate (2) was accomplished. The methodology was applied to the synthesis of a series of 2,4-disubstituted, 2,5-disubstituted, and 2,4,5-trisubstituted oxazoles.
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60
Total citations:
60
Citations from 2024:
4
(6.67%)
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MLA
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GOST
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Hodgetts K. J., Kershaw M. T. Ethyl 2-Chlorooxazole-4-carboxylate: A Versatile Intermediate for the Synthesis of Substituted Oxazoles // Organic Letters. 2002. Vol. 4. No. 17. pp. 2905-2907.
GOST all authors (up to 50)
Copy
Hodgetts K. J., Kershaw M. T. Ethyl 2-Chlorooxazole-4-carboxylate: A Versatile Intermediate for the Synthesis of Substituted Oxazoles // Organic Letters. 2002. Vol. 4. No. 17. pp. 2905-2907.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/ol0262800
UR - https://doi.org/10.1021/ol0262800
TI - Ethyl 2-Chlorooxazole-4-carboxylate: A Versatile Intermediate for the Synthesis of Substituted Oxazoles
T2 - Organic Letters
AU - Hodgetts, Kevin J.
AU - Kershaw, Mark T
PY - 2002
DA - 2002/07/23
PB - American Chemical Society (ACS)
SP - 2905-2907
IS - 17
VL - 4
PMID - 12182585
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2002_Hodgetts,
author = {Kevin J. Hodgetts and Mark T Kershaw},
title = {Ethyl 2-Chlorooxazole-4-carboxylate: A Versatile Intermediate for the Synthesis of Substituted Oxazoles},
journal = {Organic Letters},
year = {2002},
volume = {4},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/ol0262800},
number = {17},
pages = {2905--2907},
doi = {10.1021/ol0262800}
}
Cite this
MLA
Copy
Hodgetts, Kevin J., and Mark T Kershaw. “Ethyl 2-Chlorooxazole-4-carboxylate: A Versatile Intermediate for the Synthesis of Substituted Oxazoles.” Organic Letters, vol. 4, no. 17, Jul. 2002, pp. 2905-2907. https://doi.org/10.1021/ol0262800.