Diastereoselective Synthesis of Pyrrolidines Using a Nitrone/Cyclopropane Cycloaddition: Synthesis of the Tetracyclic Core of Nakadomarin A
Тип публикации: Journal Article
Дата публикации: 2005-02-01
scimago Q1
wos Q1
БС1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
15727483
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
The synthesis of the tetracyclic core of nakadomarin A is described. The core contains all the heterocycles and the required stereocenters found in the natural product and provides a promising route to the target itself. The strategy utilizes a general, diastereoselective pyrrolidine synthesis that proceeds via a homo 3 + 2 dipolar cycloaddition. The scope of this methodology is also described. [structure: see text]
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Young I. S., Williams J. L., Kerr M. A. Diastereoselective Synthesis of Pyrrolidines Using a Nitrone/Cyclopropane Cycloaddition: Synthesis of the Tetracyclic Core of Nakadomarin A // Organic Letters. 2005. Vol. 7. No. 5. pp. 953-955.
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Young I. S., Williams J. L., Kerr M. A. Diastereoselective Synthesis of Pyrrolidines Using a Nitrone/Cyclopropane Cycloaddition: Synthesis of the Tetracyclic Core of Nakadomarin A // Organic Letters. 2005. Vol. 7. No. 5. pp. 953-955.
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TY - JOUR
DO - 10.1021/ol0501018
UR - https://doi.org/10.1021/ol0501018
TI - Diastereoselective Synthesis of Pyrrolidines Using a Nitrone/Cyclopropane Cycloaddition: Synthesis of the Tetracyclic Core of Nakadomarin A
T2 - Organic Letters
AU - Young, Ian S
AU - Williams, Justin L.
AU - Kerr, M A
PY - 2005
DA - 2005/02/01
PB - American Chemical Society (ACS)
SP - 953-955
IS - 5
VL - 7
PMID - 15727483
SN - 1523-7060
SN - 1523-7052
ER -
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@article{2005_Young,
author = {Ian S Young and Justin L. Williams and M A Kerr},
title = {Diastereoselective Synthesis of Pyrrolidines Using a Nitrone/Cyclopropane Cycloaddition: Synthesis of the Tetracyclic Core of Nakadomarin A},
journal = {Organic Letters},
year = {2005},
volume = {7},
publisher = {American Chemical Society (ACS)},
month = {feb},
url = {https://doi.org/10.1021/ol0501018},
number = {5},
pages = {953--955},
doi = {10.1021/ol0501018}
}
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MLA
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Young, Ian S., et al. “Diastereoselective Synthesis of Pyrrolidines Using a Nitrone/Cyclopropane Cycloaddition: Synthesis of the Tetracyclic Core of Nakadomarin A.” Organic Letters, vol. 7, no. 5, Feb. 2005, pp. 953-955. https://doi.org/10.1021/ol0501018.