SnAP Reagents for the Synthesis of Piperazines and Morpholines
Publication type: Journal Article
Publication date: 2014-02-06
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
24502436
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Substituted piperazines and morpholines are valuable structural motifs in biologically active compounds, but are not easily prepared by contemporary cross-coupling approaches. In this report, we introduce SnAP reagents for the transformation of aldehydes into N-unprotected piperazines and morpholines. This approach offers simple, mild conditions compatible with aromatic, heteroaromatic, aliphatic, and glyoxylic aldehydes and provides mono- and disubstituted N-heterocycles in a single step.
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85
Total citations:
85
Citations from 2024:
10
(11.77%)
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MLA
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GOST
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Luescher M. U., Vo C. V. T., Bode J. W. SnAP Reagents for the Synthesis of Piperazines and Morpholines // Organic Letters. 2014. Vol. 16. No. 4. pp. 1236-1239.
GOST all authors (up to 50)
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Luescher M. U., Vo C. V. T., Bode J. W. SnAP Reagents for the Synthesis of Piperazines and Morpholines // Organic Letters. 2014. Vol. 16. No. 4. pp. 1236-1239.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/ol500210z
UR - https://doi.org/10.1021/ol500210z
TI - SnAP Reagents for the Synthesis of Piperazines and Morpholines
T2 - Organic Letters
AU - Luescher, Michael U
AU - Vo, Cam Van T
AU - Bode, Jeffrey W
PY - 2014
DA - 2014/02/06
PB - American Chemical Society (ACS)
SP - 1236-1239
IS - 4
VL - 16
PMID - 24502436
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2014_Luescher,
author = {Michael U Luescher and Cam Van T Vo and Jeffrey W Bode},
title = {SnAP Reagents for the Synthesis of Piperazines and Morpholines},
journal = {Organic Letters},
year = {2014},
volume = {16},
publisher = {American Chemical Society (ACS)},
month = {feb},
url = {https://doi.org/10.1021/ol500210z},
number = {4},
pages = {1236--1239},
doi = {10.1021/ol500210z}
}
Cite this
MLA
Copy
Luescher, Michael U., et al. “SnAP Reagents for the Synthesis of Piperazines and Morpholines.” Organic Letters, vol. 16, no. 4, Feb. 2014, pp. 1236-1239. https://doi.org/10.1021/ol500210z.