Chemical Reviews, volume 121, issue 8, pages 4678-4742
Chemical Aspects of Human and Environmental Overload with Fluorine
Jianlin Han
1
,
Lorand Kiss
2
,
Haibo Mei
1
,
Attila Márió Remete
2
,
Maja Ponikvar‑svet
3
,
Daniel M Sedgwick
4
,
Raquel Román
4
,
Santos Fustero
4
,
Hiroki Moriwaki
5
,
Vadim A. Soloshonok
6, 7
3
Department of Inorganic Chemistry and Technology, Jožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia
|
4
Departamento de Química Orgánica, Universidad de Valencia, 46100 Burjassot, Valencia Spain
|
5
Hamari Chemicals Ltd., 1-19-40, Nankokita, Suminoe-ku, Osaka 559-0034, Japan
|
Publication type: Journal Article
Publication date: 2021-03-16
Journal:
Chemical Reviews
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 62.1
ISSN: 00092665, 15206890
General Chemistry
Abstract
Over the last 100-120 years, due to the ever-increasing importance of fluorine-containing compounds in modern technology and daily life, the explosive development of the fluorochemical industry led to an enormous increase of emission of fluoride ions into the biosphere. This made it more and more important to understand the biological activities, metabolism, degradation, and possible environmental hazards of such substances. This comprehensive and critical review focuses on the effects of fluoride ions and organofluorine compounds (mainly pharmaceuticals and agrochemicals) on human health and the environment. To give a better overview, various connected topics are also discussed: reasons and trends of the advance of fluorine-containing pharmaceuticals and agrochemicals, metabolism of fluorinated drugs, withdrawn fluorinated drugs, natural sources of organic and inorganic fluorine compounds in the environment (including the biosphere), sources of fluoride intake, and finally biomarkers of fluoride exposure.
Top-30
Citations by journals
|
2
4
6
8
10
|
|
|
Journal of Organic Chemistry
10 publications, 4.22%
|
|
|
Molecules
9 publications, 3.8%
|
|
|
Journal of Fluorine Chemistry
8 publications, 3.38%
|
|
|
Chemical Engineering Journal
8 publications, 3.38%
|
|
|
Organic Letters
7 publications, 2.95%
|
|
|
Chinese Chemical Letters
6 publications, 2.53%
|
|
|
Chemical Record
6 publications, 2.53%
|
|
|
European Journal of Organic Chemistry
6 publications, 2.53%
|
|
|
Chemistry - A European Journal
6 publications, 2.53%
|
|
|
Separation and Purification Technology
5 publications, 2.11%
|
|
|
RSC Advances
5 publications, 2.11%
|
|
|
Advanced Synthesis and Catalysis
4 publications, 1.69%
|
|
|
ACS Sustainable Chemistry and Engineering
3 publications, 1.27%
|
|
|
Pharmaceuticals
3 publications, 1.27%
|
|
|
Journal of Molecular Liquids
3 publications, 1.27%
|
|
|
Journal of Molecular Structure
3 publications, 1.27%
|
|
|
Chemical Reviews
3 publications, 1.27%
|
|
|
ACS Omega
3 publications, 1.27%
|
|
|
ACS applied materials & interfaces
3 publications, 1.27%
|
|
|
Chemical Science
3 publications, 1.27%
|
|
|
Organic Chemistry Frontiers
3 publications, 1.27%
|
|
|
Science of the Total Environment
3 publications, 1.27%
|
|
|
Synthesis
3 publications, 1.27%
|
|
|
Environmental Science & Technology
3 publications, 1.27%
|
|
|
Symmetry
2 publications, 0.84%
|
|
|
Science China Chemistry
2 publications, 0.84%
|
|
|
Dyes and Pigments
2 publications, 0.84%
|
|
|
Desalination
2 publications, 0.84%
|
|
|
Ecotoxicology and Environmental Safety
2 publications, 0.84%
|
|
|
2
4
6
8
10
|
Citations by publishers
|
10
20
30
40
50
60
70
80
|
|
|
Elsevier
80 publications, 33.76%
|
|
|
American Chemical Society (ACS)
42 publications, 17.72%
|
|
|
Wiley
39 publications, 16.46%
|
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
20 publications, 8.44%
|
|
|
Royal Society of Chemistry (RSC)
18 publications, 7.59%
|
|
|
Springer Nature
15 publications, 6.33%
|
|
|
Thieme
4 publications, 1.69%
|
|
|
Frontiers Media S.A.
3 publications, 1.27%
|
|
|
Beilstein-Institut
1 publication, 0.42%
|
|
|
Bentham Science
1 publication, 0.42%
|
|
|
IOP Publishing
1 publication, 0.42%
|
|
|
American Society for Microbiology
1 publication, 0.42%
|
|
|
Hindawi Limited
1 publication, 0.42%
|
|
|
Wolters Kluwer Health
1 publication, 0.42%
|
|
|
Federal Scientific Center for Hygiene F.F.Erisman
1 publication, 0.42%
|
|
|
IWA Publishing
1 publication, 0.42%
|
|
|
Research Square Platform LLC
1 publication, 0.42%
|
|
|
South Florida Publishing LLC
1 publication, 0.42%
|
|
|
Oxford University Press
1 publication, 0.42%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 0.42%
|
|
|
10
20
30
40
50
60
70
80
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[0,0,0,0],"codes":[0,0,0,0],"imageUrls":["","","",""],"datasets":[{"label":"Citations number","data":[22,60,78,77],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["9.28","25.32","32.91","32.49"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Journal of Organic Chemistry","Molecules","Journal of Fluorine Chemistry","Chemical Engineering Journal","Organic Letters","Chinese Chemical Letters","Chemical Record","European Journal of Organic Chemistry","Chemistry - A European Journal","Separation and Purification Technology","RSC Advances","Advanced Synthesis and Catalysis","ACS Sustainable Chemistry and Engineering","Pharmaceuticals","Journal of Molecular Liquids","Journal of Molecular Structure","Chemical Reviews","ACS Omega","ACS applied materials & interfaces","Chemical Science","Organic Chemistry Frontiers","Science of the Total Environment","Synthesis","Environmental Science & Technology","Symmetry","Science China Chemistry","Dyes and Pigments","Desalination","Ecotoxicology and Environmental Safety"],"ids":[8697,1770,14755,16275,3315,20341,22413,19472,24708,21492,3100,3906,18886,1203,13597,9347,13718,18901,1458,9646,3991,2679,10934,21390,21974,14409,10101,20324,8694],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/xqixcltwJYe6H8Uco2JbAFfIOzt7UNKH0OcPOPzO_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[10,9,8,8,7,6,6,6,6,5,5,4,3,3,3,3,3,3,3,3,3,3,3,3,2,2,2,2,2],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[4.22,3.8,3.38,3.38,2.95,2.53,2.53,2.53,2.53,2.11,2.11,1.69,1.27,1.27,1.27,1.27,1.27,1.27,1.27,1.27,1.27,1.27,1.27,1.27,0.84,0.84,0.84,0.84,0.84],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","American Chemical Society (ACS)","Wiley","Multidisciplinary Digital Publishing Institute (MDPI)","Royal Society of Chemistry (RSC)","Springer Nature","Thieme","Frontiers Media S.A.","Beilstein-Institut","Bentham Science","IOP Publishing","American Society for Microbiology","Hindawi Limited","Wolters Kluwer Health","Federal Scientific Center for Hygiene F.F.Erisman","IWA Publishing","Research Square Platform LLC","South Florida Publishing LLC","Oxford University Press","Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii"],"ids":[17,40,11,202,123,8,135,208,6139,39,2075,142,6921,32,9208,1283,9418,8149,19,9422],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/xqixcltwJYe6H8Uco2JbAFfIOzt7UNKH0OcPOPzO_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/ex6KJoZujZOZFZh7jGfeHauiftuB3CI7iwJVFRDg_medium.webp","\/storage\/images\/resized\/doUaFUZdxUEQjLi1TwZjGHi8HXYNWWSk04dSC6Xh_medium.webp","\/storage\/images\/resized\/LsKy6OnmmmRGcAU6CZgWQvNiP1polbaSLNrN7zqj_medium.webp","\/storage\/images\/resized\/VPE7q24PXoHr5SS2SqfEgxccSMUxWLfZINOX60uo_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/6QE8LXWrLpkoy5A2te6hw7who46GeCoTYIstuoAz_medium.webp","\/storage\/images\/resized\/Ygto3vuKeRCqElXxbp5eT9Ps6pcMM8YHPVggrH70_medium.webp","\/storage\/images\/resized\/uGx6c1W3cHqbKXWIuICsBj3302lg4GbPWL7ng21d_medium.webp","","","\/storage\/images\/resized\/yNSijlgQghQF53VZuyFLA30CKDe4j3HK74Vtpnxa_medium.webp","\/storage\/images\/resized\/9Mus3KG1Tkd7Bwaurt8H3RwWh0CxRlGoO6ng9UK1_medium.webp"],"datasets":[{"label":"","data":[80,42,39,20,18,15,4,3,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[33.76,17.72,16.46,8.44,7.59,6.33,1.69,1.27,0.42,0.42,0.42,0.42,0.42,0.42,0.42,0.42,0.42,0.42,0.42,0.42],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartiles":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,0,0],"percentage":["0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[1,4,7,4],"percentage":["0.42","1.69","2.95","1.69"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[10,7,10,11],"percentage":["4.22","2.95","4.22","4.64"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[11,42,61,59],"percentage":["4.64","17.72","25.74","24.89"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,7,0,3],"percentage":["0","2.95","0","1.27"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by SCImago per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartilesWs":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,0,1],"percentage":["0","0","0","0.42"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[1,5,9,5],"percentage":["0.42","2.11","3.8","2.11"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[15,17,24,17],"percentage":["6.33","7.17","10.13","7.17"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[6,28,44,49],"percentage":["2.53","11.81","18.57","20.68"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,10,1,5],"percentage":["0","4.22","0.42","2.11"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by WoS per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Han J. et al. Chemical Aspects of Human and Environmental Overload with Fluorine // Chemical Reviews. 2021. Vol. 121. No. 8. pp. 4678-4742.
GOST all authors (up to 50)
Copy
Han J., Kiss L., Mei H., Remete A. M., Ponikvar‑svet M., Sedgwick D. M., Román R., Fustero S., Moriwaki H., Soloshonok V. A. Chemical Aspects of Human and Environmental Overload with Fluorine // Chemical Reviews. 2021. Vol. 121. No. 8. pp. 4678-4742.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.chemrev.0c01263
UR - https://doi.org/10.1021/acs.chemrev.0c01263
TI - Chemical Aspects of Human and Environmental Overload with Fluorine
T2 - Chemical Reviews
AU - Remete, Attila Márió
AU - Han, Jianlin
AU - Mei, Haibo
AU - Fustero, Santos
AU - Soloshonok, Vadim A.
AU - Kiss, Lorand
AU - Ponikvar‑svet, Maja
AU - Sedgwick, Daniel M
AU - Román, Raquel
AU - Moriwaki, Hiroki
PY - 2021
DA - 2021/03/16 00:00:00
PB - American Chemical Society (ACS)
SP - 4678-4742
IS - 8
VL - 121
SN - 0009-2665
SN - 1520-6890
ER -
Cite this
BibTex
Copy
@article{2021_Han,
author = {Attila Márió Remete and Jianlin Han and Haibo Mei and Santos Fustero and Vadim A. Soloshonok and Lorand Kiss and Maja Ponikvar‑svet and Daniel M Sedgwick and Raquel Román and Hiroki Moriwaki},
title = {Chemical Aspects of Human and Environmental Overload with Fluorine},
journal = {Chemical Reviews},
year = {2021},
volume = {121},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/acs.chemrev.0c01263},
number = {8},
pages = {4678--4742},
doi = {10.1021/acs.chemrev.0c01263}
}
Cite this
MLA
Copy
Han, Jianlin, et al. “Chemical Aspects of Human and Environmental Overload with Fluorine.” Chemical Reviews, vol. 121, no. 8, Mar. 2021, pp. 4678-4742. https://doi.org/10.1021/acs.chemrev.0c01263.