Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications.
1
Cardiovascular
and Metabolic Diseases, Innovative Medicines and Early Development
Biotech Unit, AstraZeneca, Pepparedsleden 1, SE-43183 Mölndal, Sweden
|
Publication type: Journal Article
Publication date: 2016-11-18
scimago Q1
wos Q1
SJR: 16.455
CiteScore: 100.5
Impact factor: 55.8
ISSN: 00092665, 15206890
PubMed ID:
27960271
General Chemistry
Abstract
The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established copper-catalyzed reaction providing the 1,4-isomer. The RuAAC reaction has quickly found its way into the organic chemistry toolbox and found applications in many different areas, such as medicinal chemistry, polymer synthesis, organocatalysis, supramolecular chemistry, and the construction of electronic devices. This Review discusses the mechanism, scope, and applications of the RuAAC reaction, covering the literature from the last 10 years.
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Metrics
357
Total citations:
357
Citations from 2024:
88
(24.65%)
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GOST
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Johansson J. et al. Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications. // Chemical Reviews. 2016. Vol. 116. No. 23. pp. 14726-14768.
GOST all authors (up to 50)
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Johansson J., Beke-Somfai T., Said Stålsmeden A., Kann N. Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications. // Chemical Reviews. 2016. Vol. 116. No. 23. pp. 14726-14768.
Cite this
RIS
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TY - JOUR
DO - 10.1021/acs.chemrev.6b00466
UR - https://doi.org/10.1021/acs.chemrev.6b00466
TI - Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications.
T2 - Chemical Reviews
AU - Johansson, Johan
AU - Beke-Somfai, Tamás
AU - Said Stålsmeden, Anna
AU - Kann, Nina
PY - 2016
DA - 2016/11/18
PB - American Chemical Society (ACS)
SP - 14726-14768
IS - 23
VL - 116
PMID - 27960271
SN - 0009-2665
SN - 1520-6890
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Johansson,
author = {Johan Johansson and Tamás Beke-Somfai and Anna Said Stålsmeden and Nina Kann},
title = {Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications.},
journal = {Chemical Reviews},
year = {2016},
volume = {116},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://doi.org/10.1021/acs.chemrev.6b00466},
number = {23},
pages = {14726--14768},
doi = {10.1021/acs.chemrev.6b00466}
}
Cite this
MLA
Copy
Johansson, Johan, et al. “Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications..” Chemical Reviews, vol. 116, no. 23, Nov. 2016, pp. 14726-14768. https://doi.org/10.1021/acs.chemrev.6b00466.