Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities
Wei Hou
1
,
Hongtao Xu
2
Publication type: Journal Article
Publication date: 2022-03-04
scimago Q1
wos Q1
SJR: 1.801
CiteScore: 11.5
Impact factor: 6.8
ISSN: 00222623, 15204804
PubMed ID:
35244394
Drug Discovery
Molecular Medicine
Abstract
Selenium (Se)-containing compounds have emerged as potential therapeutic agents for the treatment of a range of diseases. Through tremendous effort, considerable knowledge has been acquired to understand the complex chemical properties and biological activities of selenium, especially after its incorporation into bioactive molecules. From this perspective, we compiled extensive literature evidence to summarize and critically discuss the relationship between the pharmacological activities and chemical properties of selenium compounds and the strategic incorporation of selenium into organic molecules, especially bioactive heterocycles and natural products. We also provide perspectives regarding the challenges in selenium-based medicinal chemistry and future research directions.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
2
4
6
8
10
12
14
16
18
20
|
|
|
Journal of Organic Chemistry
19 publications, 7.66%
|
|
|
Journal of Medicinal Chemistry
13 publications, 5.24%
|
|
|
Organic Letters
12 publications, 4.84%
|
|
|
Organic and Biomolecular Chemistry
11 publications, 4.44%
|
|
|
European Journal of Medicinal Chemistry
9 publications, 3.63%
|
|
|
New Journal of Chemistry
9 publications, 3.63%
|
|
|
European Journal of Organic Chemistry
6 publications, 2.42%
|
|
|
Advanced Synthesis and Catalysis
6 publications, 2.42%
|
|
|
Bioorganic Chemistry
5 publications, 2.02%
|
|
|
Angewandte Chemie
5 publications, 2.02%
|
|
|
Angewandte Chemie - International Edition
5 publications, 2.02%
|
|
|
Organic Chemistry Frontiers
5 publications, 2.02%
|
|
|
Chemistry - An Asian Journal
5 publications, 2.02%
|
|
|
Chinese Chemical Letters
4 publications, 1.61%
|
|
|
Future Medicinal Chemistry
4 publications, 1.61%
|
|
|
Tetrahedron
4 publications, 1.61%
|
|
|
Chemical Engineering Journal
3 publications, 1.21%
|
|
|
ChemistrySelect
3 publications, 1.21%
|
|
|
Nature Communications
3 publications, 1.21%
|
|
|
ACS Catalysis
3 publications, 1.21%
|
|
|
Green Chemistry
3 publications, 1.21%
|
|
|
Molecules
2 publications, 0.81%
|
|
|
Journal of Inorganic Biochemistry
2 publications, 0.81%
|
|
|
International Journal of Molecular Sciences
2 publications, 0.81%
|
|
|
Chinese Journal of Chemistry
2 publications, 0.81%
|
|
|
ChemMedChem
2 publications, 0.81%
|
|
|
Chemical Science
2 publications, 0.81%
|
|
|
RSC Medicinal Chemistry
2 publications, 0.81%
|
|
|
Asian Journal of Organic Chemistry
2 publications, 0.81%
|
|
|
2
4
6
8
10
12
14
16
18
20
|
Publishers
|
10
20
30
40
50
60
70
|
|
|
Elsevier
63 publications, 25.4%
|
|
|
American Chemical Society (ACS)
59 publications, 23.79%
|
|
|
Wiley
49 publications, 19.76%
|
|
|
Royal Society of Chemistry (RSC)
35 publications, 14.11%
|
|
|
MDPI
11 publications, 4.44%
|
|
|
Springer Nature
11 publications, 4.44%
|
|
|
Taylor & Francis
8 publications, 3.23%
|
|
|
Georg Thieme Verlag KG
2 publications, 0.81%
|
|
|
AIP Publishing
1 publication, 0.4%
|
|
|
Shanghai Institute of Organic Chemistry
1 publication, 0.4%
|
|
|
Walter de Gruyter
1 publication, 0.4%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 0.4%
|
|
|
Frontiers Media S.A.
1 publication, 0.4%
|
|
|
Ovid Technologies (Wolters Kluwer Health)
1 publication, 0.4%
|
|
|
IntechOpen
1 publication, 0.4%
|
|
|
10
20
30
40
50
60
70
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
248
Total citations:
248
Citations from 2024:
167
(67.34%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Hou W., Xu H. Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities // Journal of Medicinal Chemistry. 2022. Vol. 65. No. 6. pp. 4436-4456.
GOST all authors (up to 50)
Copy
Hou W., Xu H. Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities // Journal of Medicinal Chemistry. 2022. Vol. 65. No. 6. pp. 4436-4456.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.jmedchem.1c01859
UR - https://doi.org/10.1021/acs.jmedchem.1c01859
TI - Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities
T2 - Journal of Medicinal Chemistry
AU - Hou, Wei
AU - Xu, Hongtao
PY - 2022
DA - 2022/03/04
PB - American Chemical Society (ACS)
SP - 4436-4456
IS - 6
VL - 65
PMID - 35244394
SN - 0022-2623
SN - 1520-4804
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Hou,
author = {Wei Hou and Hongtao Xu},
title = {Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities},
journal = {Journal of Medicinal Chemistry},
year = {2022},
volume = {65},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/acs.jmedchem.1c01859},
number = {6},
pages = {4436--4456},
doi = {10.1021/acs.jmedchem.1c01859}
}
Cite this
MLA
Copy
Hou, Wei, and Hongtao Xu. “Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities.” Journal of Medicinal Chemistry, vol. 65, no. 6, Mar. 2022, pp. 4436-4456. https://doi.org/10.1021/acs.jmedchem.1c01859.