From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles
Тип публикации: Journal Article
Дата публикации: 2018-07-19
scimago Q1
wos Q1
БС1
SJR: 1.801
CiteScore: 11.5
Impact factor: 6.8
ISSN: 00222623, 15204804
PubMed ID:
30024747
Drug Discovery
Molecular Medicine
Краткое описание
Oxygen heterocycles are the second most common type of heterocycles that appear as structural components of U.S. Food and Drug Administration (FDA) approved pharmaceuticals. Analysis of our database of drugs approved through 2017 reveals 311 distinct pharmaceuticals containing at least one oxygen heterocycle. Most prevalent among these are pyranoses, with furanoses, macrolactones, morpholines, and dioxolanes rounding off the top five. The main body of this Perspective is organized according to ring size, commencing with three- and four-membered rings and ending with macrocycles, polymers, and unusual oxygen-containing heterocycles. For each section, all oxygen heterocycle-containing drugs are presented along with a brief discussion about structural and drug application patterns.
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ГОСТ
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Delost M. D. et al. From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles // Journal of Medicinal Chemistry. 2018. Vol. 61. No. 24. pp. 10996-11020.
ГОСТ со всеми авторами (до 50)
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Delost M. D., Smith D. T., Anderson B. J., Njardarson J. T. From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles // Journal of Medicinal Chemistry. 2018. Vol. 61. No. 24. pp. 10996-11020.
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TY - JOUR
DO - 10.1021/acs.jmedchem.8b00876
UR - https://doi.org/10.1021/acs.jmedchem.8b00876
TI - From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles
T2 - Journal of Medicinal Chemistry
AU - Delost, Michael D
AU - Smith, David T
AU - Anderson, Benton J
AU - Njardarson, J. T.
PY - 2018
DA - 2018/07/19
PB - American Chemical Society (ACS)
SP - 10996-11020
IS - 24
VL - 61
PMID - 30024747
SN - 0022-2623
SN - 1520-4804
ER -
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BibTex (до 50 авторов)
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@article{2018_Delost,
author = {Michael D Delost and David T Smith and Benton J Anderson and J. T. Njardarson},
title = {From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles},
journal = {Journal of Medicinal Chemistry},
year = {2018},
volume = {61},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/acs.jmedchem.8b00876},
number = {24},
pages = {10996--11020},
doi = {10.1021/acs.jmedchem.8b00876}
}
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MLA
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Delost, Michael D., et al. “From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles.” Journal of Medicinal Chemistry, vol. 61, no. 24, Jul. 2018, pp. 10996-11020. https://doi.org/10.1021/acs.jmedchem.8b00876.