Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery
Publication type: Journal Article
Publication date: 2018-10-01
scimago Q1
wos Q1
SJR: 1.801
CiteScore: 11.5
Impact factor: 6.8
ISSN: 00222623, 15204804
PubMed ID:
30272973
Drug Discovery
Molecular Medicine
Abstract
The modern constraints of drug discovery demand a rigorous validation process of all new reactions prior to widespread implementation. To this end, sulfinates (now marketed as Diversinates) have seen alacritous adoption by the medicinal chemistry community, as evidenced by the recent outpour of both patent and primary reports. Featuring more than 50 examples, this review seeks to highlight those particularly compelling cases published in the past 5 years, with an eye toward the identification of robust and predictable trends in reactivity.
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Metrics
125
Total citations:
125
Citations from 2024:
30
(24%)
Cite this
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BibTex |
MLA
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GOST
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Smith J. M. et al. Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery // Journal of Medicinal Chemistry. 2018. Vol. 62. No. 5. pp. 2256-2264.
GOST all authors (up to 50)
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Smith J. M., Dixon J. A., Degruyter J. N., Baran P. S. Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery // Journal of Medicinal Chemistry. 2018. Vol. 62. No. 5. pp. 2256-2264.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.jmedchem.8b01303
UR - https://doi.org/10.1021/acs.jmedchem.8b01303
TI - Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery
T2 - Journal of Medicinal Chemistry
AU - Smith, Joel M
AU - Dixon, Janice A
AU - Degruyter, Justine N
AU - Baran, Phil S
PY - 2018
DA - 2018/10/01
PB - American Chemical Society (ACS)
SP - 2256-2264
IS - 5
VL - 62
PMID - 30272973
SN - 0022-2623
SN - 1520-4804
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_Smith,
author = {Joel M Smith and Janice A Dixon and Justine N Degruyter and Phil S Baran},
title = {Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery},
journal = {Journal of Medicinal Chemistry},
year = {2018},
volume = {62},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/acs.jmedchem.8b01303},
number = {5},
pages = {2256--2264},
doi = {10.1021/acs.jmedchem.8b01303}
}
Cite this
MLA
Copy
Smith, Joel M., et al. “Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery.” Journal of Medicinal Chemistry, vol. 62, no. 5, Oct. 2018, pp. 2256-2264. https://doi.org/10.1021/acs.jmedchem.8b01303.
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