Diastereoselective Addition of PhSCF2SiMe3 to Chiral N-tert-Butanesulfinyl Ketimines Derived from Isatins: Synthesis of Enantioenriched gem-Difluoromethylenated Spiro-pyrrolidinyl and Spiro-piperidinyl Oxindoles
Тип публикации: Journal Article
Дата публикации: 2022-11-10
SCImago Q2
WOS Q1
БС1
SJR: 0.604
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
36366856
Краткое описание
A convenient and efficient synthetic strategy to prepare enantioenriched gem-difluoromethylenated spiro-pyrrolidinyl and spiro-piperidinyl oxindoles is described. Fluoride-mediated diastereoselective nucleophilic addition of PhSCF2SiMe3 to chiral N-tert-butanesulfinyl ketimines derived from isatins was a key step and provided diastereomeric adducts, which were readily separable. Removal of the chiral sulfinyl group followed by structural manipulation afforded chiral gem-difluoromethylenated spiro-pyrrolidinyl and spiro-piperidinyl oxindoles.
Найдено
Ничего не найдено, попробуйте изменить настройки фильтра.
Для доступа к списку цитирований публикации необходимо авторизоваться.
Для доступа к списку профилей, цитирующих публикацию, необходимо авторизоваться.
Топ-30
Журналы
|
1
|
|
|
Advanced Synthesis and Catalysis
1 публикация, 14.29%
|
|
|
Chemical Science
1 публикация, 14.29%
|
|
|
Organic Letters
1 публикация, 14.29%
|
|
|
Chemistry - An Asian Journal
1 публикация, 14.29%
|
|
|
Nature Communications
1 публикация, 14.29%
|
|
|
Russian Chemical Reviews
1 публикация, 14.29%
|
|
|
Journal of the American Chemical Society
1 публикация, 14.29%
|
|
|
1
|
Издатели
|
1
2
|
|
|
Wiley
2 публикации, 28.57%
|
|
|
American Chemical Society (ACS)
2 публикации, 28.57%
|
|
|
Royal Society of Chemistry (RSC)
1 публикация, 14.29%
|
|
|
Springer Nature
1 публикация, 14.29%
|
|
|
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 публикация, 14.29%
|
|
|
1
2
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.
Вы ученый?
Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.
Войти с ORCID
Метрики
7
Всего цитирований:
7
Цитирований c 2025:
5
(71.43%)
Цитировать
ГОСТ |
RIS |
BibTex
Цитировать
ГОСТ
Скопировать
Keereewan S. et al. Diastereoselective Addition of PhSCF2SiMe3 to Chiral N-tert-Butanesulfinyl Ketimines Derived from Isatins: Synthesis of Enantioenriched gem-Difluoromethylenated Spiro-pyrrolidinyl and Spiro-piperidinyl Oxindoles // Journal of Organic Chemistry. 2022. Vol. 87. No. 23.
ГОСТ со всеми авторами (до 50)
Скопировать
Keereewan S., Kuhakarn C., Leowanawat P., Saithong S., Reutrakul V., Soorukram D. Diastereoselective Addition of PhSCF2SiMe3 to Chiral N-tert-Butanesulfinyl Ketimines Derived from Isatins: Synthesis of Enantioenriched gem-Difluoromethylenated Spiro-pyrrolidinyl and Spiro-piperidinyl Oxindoles // Journal of Organic Chemistry. 2022. Vol. 87. No. 23.
Цитировать
RIS
Скопировать
TY - JOUR
DO - 10.1021/acs.joc.2c02098
UR - https://doi.org/10.1021/acs.joc.2c02098
TI - Diastereoselective Addition of PhSCF2SiMe3 to Chiral N-tert-Butanesulfinyl Ketimines Derived from Isatins: Synthesis of Enantioenriched gem-Difluoromethylenated Spiro-pyrrolidinyl and Spiro-piperidinyl Oxindoles
T2 - Journal of Organic Chemistry
AU - Keereewan, Sirisuk
AU - Kuhakarn, Chutima
AU - Leowanawat, Pawaret
AU - Saithong, Saowanit
AU - Reutrakul, Vichai
AU - Soorukram, Darunee
PY - 2022
DA - 2022/11/10
PB - American Chemical Society (ACS)
IS - 23
VL - 87
PMID - 36366856
SN - 0022-3263
SN - 1520-6904
ER -
Цитировать
BibTex (до 50 авторов)
Скопировать
@article{2022_Keereewan,
author = {Sirisuk Keereewan and Chutima Kuhakarn and Pawaret Leowanawat and Saowanit Saithong and Vichai Reutrakul and Darunee Soorukram},
title = {Diastereoselective Addition of PhSCF2SiMe3 to Chiral N-tert-Butanesulfinyl Ketimines Derived from Isatins: Synthesis of Enantioenriched gem-Difluoromethylenated Spiro-pyrrolidinyl and Spiro-piperidinyl Oxindoles},
journal = {Journal of Organic Chemistry},
year = {2022},
volume = {87},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://doi.org/10.1021/acs.joc.2c02098},
number = {23},
doi = {10.1021/acs.joc.2c02098}
}
Ошибка в публикации?