volume 81 issue 18 pages 8343-8350

Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol

Publication typeJournal Article
Publication date2016-08-29
scimago Q2
wos Q1
SJR0.737
CiteScore6.1
Impact factor3.6
ISSN00223263, 15206904
Organic Chemistry
Abstract
The first total synthesis of resorcyclic acid lactone spiroketal citreoviranol (1) is described. The synthesis was completed in nine steps and via Sonogashira cross-coupling, gold-catalyzed cyclization, and an unusual base-induced ketalization. The relative and absolute stereochemistry of citreoviranol was unambiguously confirmed using 2D NMR spectroscopy and X-ray crystallography.
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GOST |
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GOST Copy
Quach R., Furkert D. P., Brimble M. A. Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol // Journal of Organic Chemistry. 2016. Vol. 81. No. 18. pp. 8343-8350.
GOST all authors (up to 50) Copy
Quach R., Furkert D. P., Brimble M. A. Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol // Journal of Organic Chemistry. 2016. Vol. 81. No. 18. pp. 8343-8350.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1021/acs.joc.6b01503
UR - https://doi.org/10.1021/acs.joc.6b01503
TI - Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol
T2 - Journal of Organic Chemistry
AU - Quach, Rachelle
AU - Furkert, Daniel P.
AU - Brimble, Margaret A.
PY - 2016
DA - 2016/08/29
PB - American Chemical Society (ACS)
SP - 8343-8350
IS - 18
VL - 81
PMID - 27505436
SN - 0022-3263
SN - 1520-6904
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Quach,
author = {Rachelle Quach and Daniel P. Furkert and Margaret A. Brimble},
title = {Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol},
journal = {Journal of Organic Chemistry},
year = {2016},
volume = {81},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/acs.joc.6b01503},
number = {18},
pages = {8343--8350},
doi = {10.1021/acs.joc.6b01503}
}
MLA
Cite this
MLA Copy
Quach, Rachelle, et al. “Total Synthesis of the Resorcyclic Acid Lactone Spiroketal Citreoviranol.” Journal of Organic Chemistry, vol. 81, no. 18, Aug. 2016, pp. 8343-8350. https://doi.org/10.1021/acs.joc.6b01503.