Synthesis of gem-Difluorinated Hydroxypyrrolidines.
Publication type: Journal Article
Publication date: 2017-03-02
scimago Q2
wos Q1
SJR: 0.737
CiteScore: 6.1
Impact factor: 3.6
ISSN: 00223263, 15206904
PubMed ID:
28218543
Organic Chemistry
Abstract
A method for the synthesis of 3-hydroxy-4,4-difluoropyrrolidines from α,α-difluoro-β-bromoketones is described. The reaction involves methylenation of the carbonyl group with tetrahydrothiophenium ylide followed by coupling with primary amines.
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Total citations:
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Fedorov O. V., Struchkova M. I., Dilman A. D. Synthesis of gem-Difluorinated Hydroxypyrrolidines. // Journal of Organic Chemistry. 2017. Vol. 82. No. 6. pp. 3270-3275.
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Fedorov O. V., Struchkova M. I., Dilman A. D. Synthesis of gem-Difluorinated Hydroxypyrrolidines. // Journal of Organic Chemistry. 2017. Vol. 82. No. 6. pp. 3270-3275.
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RIS
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TY - JOUR
DO - 10.1021/acs.joc.6b03033
UR - https://doi.org/10.1021/acs.joc.6b03033
TI - Synthesis of gem-Difluorinated Hydroxypyrrolidines.
T2 - Journal of Organic Chemistry
AU - Fedorov, Oleg V.
AU - Struchkova, Marina I.
AU - Dilman, Alexander D
PY - 2017
DA - 2017/03/02
PB - American Chemical Society (ACS)
SP - 3270-3275
IS - 6
VL - 82
PMID - 28218543
SN - 0022-3263
SN - 1520-6904
ER -
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BibTex (up to 50 authors)
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@article{2017_Fedorov,
author = {Oleg V. Fedorov and Marina I. Struchkova and Alexander D Dilman},
title = {Synthesis of gem-Difluorinated Hydroxypyrrolidines.},
journal = {Journal of Organic Chemistry},
year = {2017},
volume = {82},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/acs.joc.6b03033},
number = {6},
pages = {3270--3275},
doi = {10.1021/acs.joc.6b03033}
}
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MLA
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Fedorov, Oleg V., et al. “Synthesis of gem-Difluorinated Hydroxypyrrolidines..” Journal of Organic Chemistry, vol. 82, no. 6, Mar. 2017, pp. 3270-3275. https://doi.org/10.1021/acs.joc.6b03033.
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