volume 51 issue 21 pages 8530-8538

Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation

Publication typeJournal Article
Publication date2018-10-18
scimago Q1
wos Q1
SJR1.352
CiteScore9.0
Impact factor5.2
ISSN00249297, 15205835
Materials Chemistry
Organic Chemistry
Inorganic Chemistry
Polymers and Plastics
Abstract
Plasmonic vesicles combine the advantages of polymersomes and physiochemical properties of inorganic nanoparticles, exhibiting promising applications in theranostic nanovectors. However, although many of these plasmonic vesicles have been engineered as photothermal therapy (PTT) agents and drug carriers, they undergo structural destruction due to localized surface plasmon resonance (LSPR) effect. Notably, the disassembly of plasmonic vesicles leads to the burst release of encapsulated payloads and drastically decrease therapeutic efficacy. Herein, we report the fabrication of plasmonic vesicles that can be tracelessly cross-linked under 410 nm blue light irradiation, which can effectively avoid being disassembled when localized heat generation under light irradiation (e.g., 560 nm). Amphiphilic hybrid gold nanoparticles (AuNPs) functionalized with hydrophilic poly(ethylene oxide) (PEO) and hydrophobic poly(2-((((2-nitrobenzyl)oxy)carbonyl)amino)ethyl methacrylate) (PNBOC) blocks were synthesized via ligan...
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GOST Copy
Zhu K. et al. Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation // Macromolecules. 2018. Vol. 51. No. 21. pp. 8530-8538.
GOST all authors (up to 50) Copy
Zhu K., Liu G., Zhang G., Hu J., Liu S. Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation // Macromolecules. 2018. Vol. 51. No. 21. pp. 8530-8538.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.macromol.8b01653
UR - https://doi.org/10.1021/acs.macromol.8b01653
TI - Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation
T2 - Macromolecules
AU - Zhu, Kangning
AU - Liu, Guhuan
AU - Zhang, Guoying
AU - Hu, Jinming
AU - Liu, Shiyong
PY - 2018
DA - 2018/10/18
PB - American Chemical Society (ACS)
SP - 8530-8538
IS - 21
VL - 51
SN - 0024-9297
SN - 1520-5835
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Zhu,
author = {Kangning Zhu and Guhuan Liu and Guoying Zhang and Jinming Hu and Shiyong Liu},
title = {Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation},
journal = {Macromolecules},
year = {2018},
volume = {51},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021/acs.macromol.8b01653},
number = {21},
pages = {8530--8538},
doi = {10.1021/acs.macromol.8b01653}
}
MLA
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MLA Copy
Zhu, Kangning, et al. “Engineering Cross-Linkable Plasmonic Vesicles for Synergistic Chemo-Photothermal Therapy Using Orthogonal Light Irradiation.” Macromolecules, vol. 51, no. 21, Oct. 2018, pp. 8530-8538. https://doi.org/10.1021/acs.macromol.8b01653.