volume 15 issue 3 pages 768-797

Photochemical Activation of Enediyne Warheads: A Potential Tool for Targeted Antitumor Therapy

Publication typeJournal Article
Publication date2018-01-05
scimago Q1
wos Q1
SJR0.968
CiteScore7.8
Impact factor4.5
ISSN15438384, 15438392
Drug Discovery
Pharmaceutical Science
Molecular Medicine
Abstract
Spatial and temporal control over DNA cleavage by photoactivated enediynes can be complemented by additional factors such as the release of internal strain, chelation, pH changes, intramolecular H-bonds, and substituent effects. This review presents design and reactivity of photoactivated enediynes/enynes and analyses the chemical, biological, and photophysical challenges in their applications.
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GOST |
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GOST Copy
Bhattacharya P. et al. Photochemical Activation of Enediyne Warheads: A Potential Tool for Targeted Antitumor Therapy // Molecular Pharmaceutics. 2018. Vol. 15. No. 3. pp. 768-797.
GOST all authors (up to 50) Copy
Bhattacharya P., Basak A., Campbell A., Alabugin I. V. Photochemical Activation of Enediyne Warheads: A Potential Tool for Targeted Antitumor Therapy // Molecular Pharmaceutics. 2018. Vol. 15. No. 3. pp. 768-797.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.molpharmaceut.7b00911
UR - https://doi.org/10.1021/acs.molpharmaceut.7b00911
TI - Photochemical Activation of Enediyne Warheads: A Potential Tool for Targeted Antitumor Therapy
T2 - Molecular Pharmaceutics
AU - Bhattacharya, Prabuddha
AU - Basak, Amit
AU - Campbell, A
AU - Alabugin, Igor V.
PY - 2018
DA - 2018/01/05
PB - American Chemical Society (ACS)
SP - 768-797
IS - 3
VL - 15
PMID - 29303588
SN - 1543-8384
SN - 1543-8392
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Bhattacharya,
author = {Prabuddha Bhattacharya and Amit Basak and A Campbell and Igor V. Alabugin},
title = {Photochemical Activation of Enediyne Warheads: A Potential Tool for Targeted Antitumor Therapy},
journal = {Molecular Pharmaceutics},
year = {2018},
volume = {15},
publisher = {American Chemical Society (ACS)},
month = {jan},
url = {https://doi.org/10.1021/acs.molpharmaceut.7b00911},
number = {3},
pages = {768--797},
doi = {10.1021/acs.molpharmaceut.7b00911}
}
MLA
Cite this
MLA Copy
Bhattacharya, Prabuddha, et al. “Photochemical Activation of Enediyne Warheads: A Potential Tool for Targeted Antitumor Therapy.” Molecular Pharmaceutics, vol. 15, no. 3, Jan. 2018, pp. 768-797. https://doi.org/10.1021/acs.molpharmaceut.7b00911.