Organic Letters

, том 22 , издание 14 , страницы 5337-5341

Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium

Тип публикации: Journal Article

Дата публикации: 2020-07-06

American Chemical Society (ACS)

Organic Letters

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SJR: 1.007

CiteScore: 8.7

Impact factor: 5

ISSN: 15237060, 15237052

DOI: 10.1021/acs.orglett.0c01584

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PubMed ID: 32628492

Organic Chemistry

Biochemistry

Physical and Theoretical Chemistry

Краткое описание

Formicins A-C (1-3) were discovered from Streptomyces sp. associated with wood ants. The structures of 1 and 2 were elucidated as indenone thioesters bearing N-acetylcysteamine based on spectroscopic analysis. The configurations of 1-3 were determined by the analysis of ROESY correlations, the phenylglycine methyl ester method, and chemical derivatization from 3 to 2. Formicin A inhibited the growth of human triple-negative breast cancer cells by regulating the liver kinase B1-mediated AMPK signaling pathway.

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Du Y. E. et al. Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium // Organic Letters. 2020. Vol. 22. No. 14. pp. 5337-5341.

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Du Y. E., Byun W. S., Lee S., Hwang S., Shin Y. H., Shin B., Jang Y. J., Hong S., Shin J., Lee S. K., Oh D. Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium // Organic Letters. 2020. Vol. 22. No. 14. pp. 5337-5341.

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TY - JOUR

DO - 10.1021/acs.orglett.0c01584

UR - https://doi.org/10.1021/acs.orglett.0c01584

TI - Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium

T2 - Organic Letters

AU - Du, Young Eun

AU - Byun, Woong Sub

AU - Lee, Seok-Beom

AU - Hwang, Sunghoon

AU - Shin, Yern Hyerk

AU - Shin, Bora

AU - Jang, Yong Joon

AU - Hong, Suckchang

AU - Shin, Jongheon

AU - Lee, Sang Kook

AU - Oh, Dong-Chan

PY - 2020

DA - 2020/07/06

PB - American Chemical Society (ACS)

SP - 5337-5341

IS - 14

VL - 22

PMID - 32628492

SN - 1523-7060

SN - 1523-7052

ER -

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@article{2020_Du,

author = {Young Eun Du and Woong Sub Byun and Seok-Beom Lee and Sunghoon Hwang and Yern Hyerk Shin and Bora Shin and Yong Joon Jang and Suckchang Hong and Jongheon Shin and Sang Kook Lee and Dong-Chan Oh},

title = {Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium},

journal = {Organic Letters},

year = {2020},

volume = {22},

publisher = {American Chemical Society (ACS)},

month = {jul},

url = {https://doi.org/10.1021/acs.orglett.0c01584},

number = {14},

pages = {5337--5341},

doi = {10.1021/acs.orglett.0c01584}

}

MLA

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Du, Young Eun, et al. “Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium.” Organic Letters, vol. 22, no. 14, Jul. 2020, pp. 5337-5341. https://doi.org/10.1021/acs.orglett.0c01584.

Издатель

American Chemical Society (ACS)

Журнал

Organic Letters

SCImago Q1

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