volume 23 issue 6 pages 2375-2379

Iron-Catalyzed Regio- and Stereoselective Hydrosilylation of 1,3-Enynes To Access 1,3-Dienylsilanes

Publication typeJournal Article
Publication date2021-03-10
scimago Q1
wos Q1
SJR1.235
CiteScore8.7
Impact factor5.0
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A regio- and stereoselective hydrosilylation of 1,3-enynes with primary and secondary silanes to access 1,3-dienylsilanes is accomplished by employing an iron precatalyst bearing iminopyridine-oxazoline (IPO) ligand. The hydrosilylation proceeds via syn-addition of a Si-H bond to the alkyne group of 1,3-enynes, incorporating the silyl group at the site proximal to the alkene. The reaction features mild conditions, broad substrate scope, and good functional group tolerance. The synthetic utility was demonstrated by gram-scale reactions and further transformations.
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GOST |
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GOST Copy
Guo Z. et al. Iron-Catalyzed Regio- and Stereoselective Hydrosilylation of 1,3-Enynes To Access 1,3-Dienylsilanes // Organic Letters. 2021. Vol. 23. No. 6. pp. 2375-2379.
GOST all authors (up to 50) Copy
Guo Z., Wen H., Liu G., Huang Z. Iron-Catalyzed Regio- and Stereoselective Hydrosilylation of 1,3-Enynes To Access 1,3-Dienylsilanes // Organic Letters. 2021. Vol. 23. No. 6. pp. 2375-2379.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.1c00670
UR - https://doi.org/10.1021/acs.orglett.1c00670
TI - Iron-Catalyzed Regio- and Stereoselective Hydrosilylation of 1,3-Enynes To Access 1,3-Dienylsilanes
T2 - Organic Letters
AU - Guo, Zhihao
AU - Wen, Huanan
AU - Liu, Guixia
AU - Huang, Zheng
PY - 2021
DA - 2021/03/10
PB - American Chemical Society (ACS)
SP - 2375-2379
IS - 6
VL - 23
PMID - 33689387
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2021_Guo,
author = {Zhihao Guo and Huanan Wen and Guixia Liu and Zheng Huang},
title = {Iron-Catalyzed Regio- and Stereoselective Hydrosilylation of 1,3-Enynes To Access 1,3-Dienylsilanes},
journal = {Organic Letters},
year = {2021},
volume = {23},
publisher = {American Chemical Society (ACS)},
month = {mar},
url = {https://doi.org/10.1021/acs.orglett.1c00670},
number = {6},
pages = {2375--2379},
doi = {10.1021/acs.orglett.1c00670}
}
MLA
Cite this
MLA Copy
Guo, Zhihao, et al. “Iron-Catalyzed Regio- and Stereoselective Hydrosilylation of 1,3-Enynes To Access 1,3-Dienylsilanes.” Organic Letters, vol. 23, no. 6, Mar. 2021, pp. 2375-2379. https://doi.org/10.1021/acs.orglett.1c00670.