Synthetic Studies toward the Berkeleyacetal Core Architecture
Publication type: Journal Article
Publication date: 2021-11-15
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
34780201
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
Berkeleyacetals are structurally complex natural products that have shown potent anti-inflammatory activity. The presence of a highly dense oxygen functionality and a polycyclic ring system presents significant synthetic challenges. Herein, we report an efficient strategy for the construction of the tetracyclic core system of berkeleyacetal. Our synthetic strategy features two cycloadditions ([4+2] and [5+2]) to forge the tetracyclic core and Achmatowicz rearrangement for the preparation of the cyclization substrates containing B and E rings.
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9
Total citations:
9
Citations from 2025:
1
(11.11%)
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GOST
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Márquez Cadena M. A., Wei Y., Tong R. Synthetic Studies toward the Berkeleyacetal Core Architecture // Organic Letters. 2021. Vol. 23. No. 23. pp. 9227-9231.
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Márquez Cadena M. A., Wei Y., Tong R. Synthetic Studies toward the Berkeleyacetal Core Architecture // Organic Letters. 2021. Vol. 23. No. 23. pp. 9227-9231.
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RIS
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TY - JOUR
DO - 10.1021/acs.orglett.1c03559
UR - https://doi.org/10.1021/acs.orglett.1c03559
TI - Synthetic Studies toward the Berkeleyacetal Core Architecture
T2 - Organic Letters
AU - Márquez Cadena, Miguel Adrián
AU - Wei, Yi-ping
AU - Tong, Rong-Biao
PY - 2021
DA - 2021/11/15
PB - American Chemical Society (ACS)
SP - 9227-9231
IS - 23
VL - 23
PMID - 34780201
SN - 1523-7060
SN - 1523-7052
ER -
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BibTex (up to 50 authors)
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@article{2021_Márquez Cadena,
author = {Miguel Adrián Márquez Cadena and Yi-ping Wei and Rong-Biao Tong},
title = {Synthetic Studies toward the Berkeleyacetal Core Architecture},
journal = {Organic Letters},
year = {2021},
volume = {23},
publisher = {American Chemical Society (ACS)},
month = {nov},
url = {https://doi.org/10.1021/acs.orglett.1c03559},
number = {23},
pages = {9227--9231},
doi = {10.1021/acs.orglett.1c03559}
}
Cite this
MLA
Copy
Márquez Cadena, Miguel Adrián, et al. “Synthetic Studies toward the Berkeleyacetal Core Architecture.” Organic Letters, vol. 23, no. 23, Nov. 2021, pp. 9227-9231. https://doi.org/10.1021/acs.orglett.1c03559.