Organic Letters, volume 24, issue 42, pages 7717-7721
Sodium Hypophosphite as a Bulk and Environmentally Friendly Reducing Agent in the Reductive Amination
Kliuev Fedor S
1, 2
,
Kuznetsov Anton
3
,
Afanasyev Oleg I
1
,
Runikhina Sofiya A
1
,
Kuchuk Ekaterina
1
,
Podyacheva Evgeniya
1, 2
,
Chusov Denis
1, 4
3
Moscow South-Eastern School named after V.I. Chuikov (Moscow Chemical Lyceum), Tamozhenniy proezd 4, Moscow 111033, Russian Federation
|
Publication type: Journal Article
Publication date: 2022-10-14
Journal:
Organic Letters
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 5.2
ISSN: 15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
NaH2PO2 was found to promote reductive amination. Being nontoxic, stable, environmentally benign, and available in bulk amounts, this reducing agent showed a powerful potential to compete with classical reductants applied in the target process. An E factor of 1 was achieved for the substrate scope. Different carbonyl compounds reacted with amines under the developed conditions. The reaction demonstrated a great compatibility with a wide range of functional groups. Reaction conditions were scaled up to 200-fold.
Citations by journals
|
1
2
|
|
|
New Journal of Chemistry
|
New Journal of Chemistry
2 publications, 50%
|
|
Journal of Catalysis
|
Journal of Catalysis
1 publication, 25%
|
|
Organic and Biomolecular Chemistry
|
Organic and Biomolecular Chemistry
1 publication, 25%
|
|
1
2
|
Citations by publishers
|
1
2
3
|
|
|
Royal Society of Chemistry (RSC)
|
Royal Society of Chemistry (RSC)
3 publications, 75%
|
|
Elsevier
|
Elsevier
1 publication, 25%
|
|
1
2
3
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2023],"ids":[0],"codes":[0],"imageUrls":[""],"datasets":[{"label":"Citations number","data":[4],"backgroundColor":["#3B82F6"],"percentage":["100"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["New Journal of Chemistry","Journal of Catalysis","Organic and Biomolecular Chemistry"],"ids":[1404,20883,541],"codes":[0,0,0],"imageUrls":["\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp"],"datasets":[{"label":"","data":[2,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":[50,25,25],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Royal Society of Chemistry (RSC)","Elsevier"],"ids":[123,17],"codes":[0,0],"imageUrls":["\/storage\/images\/resized\/leiAYcRDGTSl5B1eCnwpSGqmDEUEfDPPoYisFGhT_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[3,1],"backgroundColor":["#3B82F6","#3B82F6"],"percentage":[75,25],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Kliuev F. S. et al. Sodium Hypophosphite as a Bulk and Environmentally Friendly Reducing Agent in the Reductive Amination // Organic Letters. 2022. Vol. 24. No. 42. pp. 7717-7721.
GOST all authors (up to 50)
Copy
Kliuev F. S., Kuznetsov A., Afanasyev O. I., Runikhina S. A., Kuchuk E., Podyacheva E., Tsygankov A. A., Chusov D. Sodium Hypophosphite as a Bulk and Environmentally Friendly Reducing Agent in the Reductive Amination // Organic Letters. 2022. Vol. 24. No. 42. pp. 7717-7721.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.orglett.2c02807
UR - https://doi.org/10.1021%2Facs.orglett.2c02807
TI - Sodium Hypophosphite as a Bulk and Environmentally Friendly Reducing Agent in the Reductive Amination
T2 - Organic Letters
AU - Kliuev, Fedor S
AU - Kuznetsov, Anton
AU - Afanasyev, Oleg I
AU - Runikhina, Sofiya A
AU - Kuchuk, Ekaterina
AU - Podyacheva, Evgeniya
AU - Tsygankov, Alexey A
AU - Chusov, Denis
PY - 2022
DA - 2022/10/14 00:00:00
PB - American Chemical Society (ACS)
SP - 7717-7721
IS - 42
VL - 24
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex
Copy
@article{2022_Kliuev,
author = {Fedor S Kliuev and Anton Kuznetsov and Oleg I Afanasyev and Sofiya A Runikhina and Ekaterina Kuchuk and Evgeniya Podyacheva and Alexey A Tsygankov and Denis Chusov},
title = {Sodium Hypophosphite as a Bulk and Environmentally Friendly Reducing Agent in the Reductive Amination},
journal = {Organic Letters},
year = {2022},
volume = {24},
publisher = {American Chemical Society (ACS)},
month = {oct},
url = {https://doi.org/10.1021%2Facs.orglett.2c02807},
number = {42},
pages = {7717--7721},
doi = {10.1021/acs.orglett.2c02807}
}
Cite this
MLA
Copy
Kliuev, Fedor S., et al. “Sodium Hypophosphite as a Bulk and Environmentally Friendly Reducing Agent in the Reductive Amination.” Organic Letters, vol. 24, no. 42, Oct. 2022, pp. 7717-7721. https://doi.org/10.1021%2Facs.orglett.2c02807.