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Lab team

Our group has proposed the concept of reducing addition without an external hydrogen source. The concept is to use carbon monoxide as a reducing agent. One of the reagents (amine, amide, carboxylic acid, CH fragment) acts as a hydrogen source. By avoiding the need to use an external hydrogen source, we were able to create methods that do not affect functional and protective groups. Moreover, it was possible to carry out transformations that were not previously possible due to the hydrogenation of the initial reagents. The approach also solves the problem of carbon monoxide disposal. The developed approaches are used for the synthesis of medicines, natural compounds and preparations for the needs of the agro-industrial complex. New selective reactions of carbon-nitrogen bond formation (production of amines, amides, heterocycles) carbon-carbon (production of carboxylic acids and their esters, nitriles), carbon-oxygen (production of esters and esters). In parallel, homogeneous and heterogeneous catalysts are being developed and their activity in carbon-carbon, carbon-nitrogen, carbon-oxygen bond formation reactions is being studied. The band's staff is very young and friendly. All graduate students defend their dissertations on time. On average, the total impact factor of journals for a graduate student who completed a dissertation research in our group is more than 25.

  1. NMR spectroscopy
  2. Gas chromatography–mass spectrometry (GC–MS)
  3. High-efficiency liquid chromatography (HPLC)
Chusov, Denis A
Denis Chusov
Head of Laboratory
Afanasyev, Oleg I
Oleg Afanasyev
Senior Researcher

Research directions

Reduction reactions without an external hydrogen source

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Reduction reactions without an external hydrogen source
Reduction without an external hydrogen source avoids hydrogenation of functional and protective groups

Publications and patents

Андрей Сергеевич Козлов, София Александровна Рунихина, Олег Ильич Афанасьев, Денис Александрович Чусов
RU2807017, 2023
Екатерина Александровна Кучук, Олег Ильич Афанасьев, Денис Александрович Чусов
RU2739376, 2020
Benjamin List, Denis Alexandrovich CHUSOV
US20150315140A1, 2015
Денис Александрович Чусов, София Александровна Рунихина
RU2658019, 2018
Павел Николаевич Колесников, Денис Александрович Чусов, Олег Ильич Афанасьев, Виктор Иванович Малеев
RU2620269, 2017
Виктор Иванович Малеев, Денис Александрович Чусов, Павел Николаевич Колесников
RU2547141, 2015
Виктор Иванович Малеев, Денис Александрович Чусов, Павел Николаевич Колесников
Ru2544859, 2015

Lab address

Москва, ул. Вавилова, 28
Authorization required.