Organic Letters, volume 17, issue 11, pages 2724-2727
Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone
Publication type: Journal Article
Publication date: 2015-05-26
Journal:
Organic Letters
Q1
Q1
SJR: 1.245
CiteScore: 9.3
Impact factor: 4.9
ISSN: 15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A metal-free hydroxyalkylation-initiated radical six-membered heterocycle formation reaction of N-allylbenzamide is developed. This reaction proceeds through C(sp3)–H bond cleavage, oxyalkylation of the double bond, and intramolecular cyclization, which provides a new route toward 4-substituted 3,4-dihydroisoquinolin-1(2H)-one derivatives.
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Zhou W. et al. Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone // Organic Letters. 2015. Vol. 17. No. 11. pp. 2724-2727.
GOST all authors (up to 50)
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Zhou W., Ni S., Mei H., Han J., Pan Y. Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone // Organic Letters. 2015. Vol. 17. No. 11. pp. 2724-2727.
Cite this
RIS
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TY - JOUR
DO - 10.1021/acs.orglett.5b01140
UR - https://doi.org/10.1021/acs.orglett.5b01140
TI - Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone
T2 - Organic Letters
AU - Zhou, Wei
AU - Ni, Shengyang
AU - Mei, Haibo
AU - Han, Jianlin
AU - Pan, Yi
PY - 2015
DA - 2015/05/26
PB - American Chemical Society (ACS)
SP - 2724-2727
IS - 11
VL - 17
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
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@article{2015_Zhou,
author = {Wei Zhou and Shengyang Ni and Haibo Mei and Jianlin Han and Yi Pan},
title = {Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone},
journal = {Organic Letters},
year = {2015},
volume = {17},
publisher = {American Chemical Society (ACS)},
month = {may},
url = {https://doi.org/10.1021/acs.orglett.5b01140},
number = {11},
pages = {2724--2727},
doi = {10.1021/acs.orglett.5b01140}
}
Cite this
MLA
Copy
Zhou, Wei, et al. “Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone.” Organic Letters, vol. 17, no. 11, May. 2015, pp. 2724-2727. https://doi.org/10.1021/acs.orglett.5b01140.