Organic Letters, volume 17, issue 11, pages 2724-2727

Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone

Publication typeJournal Article
Publication date2015-05-26
Journal: Organic Letters
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5.2
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A metal-free hydroxyalkylation-initiated radical six-membered heterocycle formation reaction of N-allylbenzamide is developed. This reaction proceeds through C(sp3)–H bond cleavage, oxyalkylation of the double bond, and intramolecular cyclization, which provides a new route toward 4-substituted 3,4-dihydroisoquinolin-1(2H)-one derivatives.

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GOST |
Cite this
GOST Copy
Zhou W. et al. Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone // Organic Letters. 2015. Vol. 17. No. 11. pp. 2724-2727.
GOST all authors (up to 50) Copy
Zhou W., Ni S., Mei H., Han J., Pan Y. Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone // Organic Letters. 2015. Vol. 17. No. 11. pp. 2724-2727.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.5b01140
UR - https://doi.org/10.1021/acs.orglett.5b01140
TI - Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone
T2 - Organic Letters
AU - Pan, Yi
AU - Zhou, Wei
AU - Ni, Shengyang
AU - Mei, Haibo
AU - Han, Jianlin
PY - 2015
DA - 2015/05/26 00:00:00
PB - American Chemical Society (ACS)
SP - 2724-2727
IS - 11
VL - 17
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex Copy
@article{2015_Zhou,
author = {Yi Pan and Wei Zhou and Shengyang Ni and Haibo Mei and Jianlin Han},
title = {Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone},
journal = {Organic Letters},
year = {2015},
volume = {17},
publisher = {American Chemical Society (ACS)},
month = {may},
url = {https://doi.org/10.1021/acs.orglett.5b01140},
number = {11},
pages = {2724--2727},
doi = {10.1021/acs.orglett.5b01140}
}
MLA
Cite this
MLA Copy
Zhou, Wei, et al. “Hydroxyalkylation-Initiated Radical Cyclization of N-Allylbenzamide for Direct Construction of Isoquinolinone.” Organic Letters, vol. 17, no. 11, May. 2015, pp. 2724-2727. https://doi.org/10.1021/acs.orglett.5b01140.
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