A Straightforward Approach toward Multifunctionalized Pyridazines via Imination/Electrocyclization
Тип публикации: Journal Article
Дата публикации: 2015-07-09
scimago Q1
wos Q1
БС1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5
ISSN: 15237060, 15237052
PubMed ID:
26158207
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Краткое описание
A facile synthesis of functionalized 3-carbamide pyridazines starting from readily available chlorovinyl aldehydes and oxamic acid thiohydrazides via cascade imination/electrocyclization is reported. In the presence of p-toluenesulfuric acid, various ketones have been efficiently incorporated into the pyridazine derivatives through a two-step sequence involving a Vilsmeier-Haack reaction and imination. The synthetic value of this method has been demonstrated by efficient synthesis of steroidal pyridazines.
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ГОСТ
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Komkov A. V. et al. A Straightforward Approach toward Multifunctionalized Pyridazines via Imination/Electrocyclization // Organic Letters. 2015. Vol. 17. No. 15. pp. 3734-3737.
ГОСТ со всеми авторами (до 50)
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Komkov A. V., Komendantova A. S., Menchikov L. G., Chernoburova E. I., Volkova Y., Zavarzin I. V. A Straightforward Approach toward Multifunctionalized Pyridazines via Imination/Electrocyclization // Organic Letters. 2015. Vol. 17. No. 15. pp. 3734-3737.
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TY - JOUR
DO - 10.1021/acs.orglett.5b01718
UR - https://doi.org/10.1021/acs.orglett.5b01718
TI - A Straightforward Approach toward Multifunctionalized Pyridazines via Imination/Electrocyclization
T2 - Organic Letters
AU - Komkov, Alexander V
AU - Komendantova, Anna S
AU - Menchikov, Leonid G
AU - Chernoburova, Elena I
AU - Volkova, Yulia
AU - Zavarzin, Igor V.
PY - 2015
DA - 2015/07/09
PB - American Chemical Society (ACS)
SP - 3734-3737
IS - 15
VL - 17
PMID - 26158207
SN - 1523-7060
SN - 1523-7052
ER -
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BibTex (до 50 авторов)
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@article{2015_Komkov,
author = {Alexander V Komkov and Anna S Komendantova and Leonid G Menchikov and Elena I Chernoburova and Yulia Volkova and Igor V. Zavarzin},
title = {A Straightforward Approach toward Multifunctionalized Pyridazines via Imination/Electrocyclization},
journal = {Organic Letters},
year = {2015},
volume = {17},
publisher = {American Chemical Society (ACS)},
month = {jul},
url = {https://doi.org/10.1021/acs.orglett.5b01718},
number = {15},
pages = {3734--3737},
doi = {10.1021/acs.orglett.5b01718}
}
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MLA
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Komkov, Alexander V., et al. “A Straightforward Approach toward Multifunctionalized Pyridazines via Imination/Electrocyclization.” Organic Letters, vol. 17, no. 15, Jul. 2015, pp. 3734-3737. https://doi.org/10.1021/acs.orglett.5b01718.