volume 17 issue 17 pages 4272-4275

Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones

Publication typeJournal Article
Publication date2015-08-20
scimago Q1
wos Q1
SJR1.235
CiteScore8.7
Impact factor5.0
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A visible-light-promoted regioselective denitrogenative insertion of terminal alkynes into 1,2,3-benzotriazinones is reported. This mechanistically novel process allows the synthesis of substituted isoquinolones in satisfactory isolated yields (24 examples, 46-84% yield) at room temperature under visible-light irradiation with the assistance of a photocatalyst. The proposed single-electron-transfer pathway was supported by TEMPO trapping, radical clock experiments, and Stern-Volmer analysis.
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GOST Copy
Wang H., Yu S. Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones // Organic Letters. 2015. Vol. 17. No. 17. pp. 4272-4275.
GOST all authors (up to 50) Copy
Wang H., Yu S. Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones // Organic Letters. 2015. Vol. 17. No. 17. pp. 4272-4275.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.5b01960
UR - https://doi.org/10.1021/acs.orglett.5b01960
TI - Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones
T2 - Organic Letters
AU - Wang, Hao
AU - Yu, Shouyun
PY - 2015
DA - 2015/08/20
PB - American Chemical Society (ACS)
SP - 4272-4275
IS - 17
VL - 17
PMID - 26291343
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2015_Wang,
author = {Hao Wang and Shouyun Yu},
title = {Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones},
journal = {Organic Letters},
year = {2015},
volume = {17},
publisher = {American Chemical Society (ACS)},
month = {aug},
url = {https://doi.org/10.1021/acs.orglett.5b01960},
number = {17},
pages = {4272--4275},
doi = {10.1021/acs.orglett.5b01960}
}
MLA
Cite this
MLA Copy
Wang, Hao, and Shouyun Yu. “Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones.” Organic Letters, vol. 17, no. 17, Aug. 2015, pp. 4272-4275. https://doi.org/10.1021/acs.orglett.5b01960.