Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne Insertion
Publication type: Journal Article
Publication date: 2016-12-01
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
27978695
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A palladium-catalyzed spirocyclization forming spirooxindoles and spirodihydrobenzofurans has been achieved. Mechanistic studies suggest that the transformation proceeds through sequential carbopalladation, C-H activation, and benzyne insertion. Both classes of spirocycles have been synthesized in good to excellent yields, and the procedure is readily scalable.
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Metrics
123
Total citations:
123
Citations from 2024:
19
(15.45%)
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MLA
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GOST
Copy
Yoon H. et al. Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne Insertion // Organic Letters. 2016. Vol. 18. No. 24. pp. 6324-6327.
GOST all authors (up to 50)
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Yoon H., Lossouarn A., Landau F., Petrone D. A. Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne Insertion // Organic Letters. 2016. Vol. 18. No. 24. pp. 6324-6327.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.orglett.6b03213
UR - https://doi.org/10.1021/acs.orglett.6b03213
TI - Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne Insertion
T2 - Organic Letters
AU - Yoon, Hyung
AU - Lossouarn, Alexis
AU - Landau, Felicitas
AU - Petrone, David A.
PY - 2016
DA - 2016/12/01
PB - American Chemical Society (ACS)
SP - 6324-6327
IS - 24
VL - 18
PMID - 27978695
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Yoon,
author = {Hyung Yoon and Alexis Lossouarn and Felicitas Landau and David A. Petrone},
title = {Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne Insertion},
journal = {Organic Letters},
year = {2016},
volume = {18},
publisher = {American Chemical Society (ACS)},
month = {dec},
url = {https://doi.org/10.1021/acs.orglett.6b03213},
number = {24},
pages = {6324--6327},
doi = {10.1021/acs.orglett.6b03213}
}
Cite this
MLA
Copy
Yoon, Hyung, et al. “Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne Insertion.” Organic Letters, vol. 18, no. 24, Dec. 2016, pp. 6324-6327. https://doi.org/10.1021/acs.orglett.6b03213.
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