volume 20 issue 9 pages 2543-2546

Highly Selective Pd-Catalyzed Direct C–F Bond Arylation of Polyfluoroarenes

Publication typeJournal Article
Publication date2018-04-18
scimago Q1
wos Q1
SJR1.235
CiteScore8.7
Impact factor5.0
ISSN15237060, 15237052
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A directing-group-free palladium-catalyzed direct arylation of simple polyfluoroarenes with arylboronic acids through selective C-F bond activation is described. The combination of Pd(OAc)2 with BrettPhos was identified as an efficient catalytic system to promote the reaction with high regioselectivity and broad substrate scope. Preliminary mechanistic studies reveal that the oxidative addition of Pd to the C-F bond is involved in the catalytic cycle.
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GOST |
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GOST Copy
Luo Z. J., Zhao H., Zhang X. Highly Selective Pd-Catalyzed Direct C–F Bond Arylation of Polyfluoroarenes // Organic Letters. 2018. Vol. 20. No. 9. pp. 2543-2546.
GOST all authors (up to 50) Copy
Luo Z. J., Zhao H., Zhang X. Highly Selective Pd-Catalyzed Direct C–F Bond Arylation of Polyfluoroarenes // Organic Letters. 2018. Vol. 20. No. 9. pp. 2543-2546.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1021/acs.orglett.8b00692
UR - https://doi.org/10.1021/acs.orglett.8b00692
TI - Highly Selective Pd-Catalyzed Direct C–F Bond Arylation of Polyfluoroarenes
T2 - Organic Letters
AU - Luo, Zhi Ji
AU - Zhao, Hai-Yang
AU - Zhang, Xingang
PY - 2018
DA - 2018/04/18
PB - American Chemical Society (ACS)
SP - 2543-2546
IS - 9
VL - 20
PMID - 29667829
SN - 1523-7060
SN - 1523-7052
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Luo,
author = {Zhi Ji Luo and Hai-Yang Zhao and Xingang Zhang},
title = {Highly Selective Pd-Catalyzed Direct C–F Bond Arylation of Polyfluoroarenes},
journal = {Organic Letters},
year = {2018},
volume = {20},
publisher = {American Chemical Society (ACS)},
month = {apr},
url = {https://doi.org/10.1021/acs.orglett.8b00692},
number = {9},
pages = {2543--2546},
doi = {10.1021/acs.orglett.8b00692}
}
MLA
Cite this
MLA Copy
Luo, Zhi Ji, et al. “Highly Selective Pd-Catalyzed Direct C–F Bond Arylation of Polyfluoroarenes.” Organic Letters, vol. 20, no. 9, Apr. 2018, pp. 2543-2546. https://doi.org/10.1021/acs.orglett.8b00692.