Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles.
Andy Yen
1
,
Publication type: Journal Article
Publication date: 2018-06-29
scimago Q1
wos Q1
SJR: 1.235
CiteScore: 8.7
Impact factor: 5.0
ISSN: 15237060, 15237052
PubMed ID:
29956936
Organic Chemistry
Biochemistry
Physical and Theoretical Chemistry
Abstract
A nickel-catalyzed arylcyanation reaction for the synthesis of 3,3-disubstituted oxindoles has been developed. This method features a bench-stable precatalyst system and serves as an economical alternative to the existing palladium-catalyzed arylcyanations described to date. A wide scope of oxindole products were accessible in moderate to good yields, and the rich chemistry of the newly installed nitrile functional group was demonstrated in the synthesis of various oxindole derivatives.
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37
Total citations:
37
Citations from 2025:
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(5.41%)
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GOST
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Yen A., Lautens M. Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles. // Organic Letters. 2018. Vol. 20. No. 14. pp. 4323-4327.
GOST all authors (up to 50)
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Yen A., Lautens M. Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles. // Organic Letters. 2018. Vol. 20. No. 14. pp. 4323-4327.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1021/acs.orglett.8b01772
UR - https://doi.org/10.1021/acs.orglett.8b01772
TI - Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles.
T2 - Organic Letters
AU - Yen, Andy
AU - Lautens, Mark
PY - 2018
DA - 2018/06/29
PB - American Chemical Society (ACS)
SP - 4323-4327
IS - 14
VL - 20
PMID - 29956936
SN - 1523-7060
SN - 1523-7052
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2018_Yen,
author = {Andy Yen and Mark Lautens},
title = {Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles.},
journal = {Organic Letters},
year = {2018},
volume = {20},
publisher = {American Chemical Society (ACS)},
month = {jun},
url = {https://doi.org/10.1021/acs.orglett.8b01772},
number = {14},
pages = {4323--4327},
doi = {10.1021/acs.orglett.8b01772}
}
Cite this
MLA
Copy
Yen, Andy, and Mark Lautens. “Nickel-Catalyzed Intramolecular Arylcyanation for the Synthesis of 3,3-Disubstituted Oxindoles..” Organic Letters, vol. 20, no. 14, Jun. 2018, pp. 4323-4327. https://doi.org/10.1021/acs.orglett.8b01772.
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