Organic Letters

, volume 20 , issue 16 , pages 4907-4911

Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting

Ben L. Feringa ¹

Lucie Muchov?? ²

Libor Vitek ²

Petr Klán ¹

Hide authors affiliations Show authors affiliations: 2 affiliations

Department of Chemistry and RECETOX, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic |

Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University, Na Bojišti 3, 121 08 Praha 2, Czech Republic |

Publication type: Journal Article

Publication date: 2018-07-31

American Chemical Society (ACS)

Organic Letters

scimago Q1

wos Q1

SJR: 1.235

CiteScore: 8.7

Impact factor: 5.0

ISSN: 15237060, 15237052

DOI: 10.1021/acs.orglett.8b02043

Copy DOI

PubMed ID: 30062897

Organic Chemistry

Biochemistry

Physical and Theoretical Chemistry

Abstract

The synthesis and photochemical properties of H2S-releasing BODIPY thiocarbamate photocage scaffolds activatable by visible-to-NIR (up to 700 nm) light to release carbonyl sulfide (COS), which is transformed to H2S using either isolated or natural carbonic anhydrase, is reported. The excellent uncaging cross section and high H2S release yields in in vitro experiments, including live-cell imaging, suggest that these photocages can serve as a platform for the bio-orthogonal phototriggered release within the tissue-transparent window.

Found

1 citation

Beloglazkina Elena

DSc in Chemistry, professor

297 publications, 3 268 citations, 11 reviews

h-index: 29

Lomonosov Moscow State University

1 citation

Krasnovskaya Olga

53 publications, 883 citations, 10 reviews

h-index: 17

Lomonosov Moscow State University

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GOST |

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GOST Copy

Feringa B. L. et al. Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting // Organic Letters. 2018. Vol. 20. No. 16. pp. 4907-4911.

GOST all authors (up to 50) Copy

Feringa B. L., Muchov?? L., Vitek L., Klán P. Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting // Organic Letters. 2018. Vol. 20. No. 16. pp. 4907-4911.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1021/acs.orglett.8b02043

UR - https://doi.org/10.1021/acs.orglett.8b02043

TI - Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting

T2 - Organic Letters

AU - Feringa, Ben L.

AU - Muchov??, Lucie

AU - Vitek, Libor

AU - Klán, Petr

PY - 2018

DA - 2018/07/31

PB - American Chemical Society (ACS)

SP - 4907-4911

IS - 16

VL - 20

PMID - 30062897

SN - 1523-7060

SN - 1523-7052

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2018_Feringa,

author = {Ben L. Feringa and Lucie Muchov?? and Libor Vitek and Petr Klán},

title = {Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting},

journal = {Organic Letters},

year = {2018},

volume = {20},

publisher = {American Chemical Society (ACS)},

month = {jul},

url = {https://doi.org/10.1021/acs.orglett.8b02043},

number = {16},

pages = {4907--4911},

doi = {10.1021/acs.orglett.8b02043}

}

MLA

Cite this

MLA Copy

Feringa, Ben L., et al. “Visible to NIR Light Photoactivation of Hydrogen Sulfide for Biological Targeting.” Organic Letters, vol. 20, no. 16, Jul. 2018, pp. 4907-4911. https://doi.org/10.1021/acs.orglett.8b02043.

Publisher

American Chemical Society (ACS)

Journal

Organic Letters

scimago Q1

wos Q1

SJR

1.235

CiteScore

8.7

Impact factor

5.0

ISSN

15237060 (Print)

15237052 (Electronic)